Date published: 2025-10-25

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TMEM182 Inhibitors

TMEM182 inhibitors represent a class of chemical compounds that specifically target and inhibit the activity of the transmembrane protein 182 (TMEM182). TMEM182 is a protein encoded by the TMEM182 gene, and it is characterized by its presence in cellular membranes, where it plays a role in various intracellular processes. The inhibitors of TMEM182 are designed to modulate the function of this protein by binding to it and altering its conformational state or preventing its normal interaction with other molecules in the cell. These inhibitors are typically small organic compounds that can interact with specific domains of the TMEM182 protein, thereby altering its structural and functional properties. The exact mechanisms of inhibition may vary depending on the structure of the inhibitor and its binding affinity for the protein.

Inhibitors of TMEM182 can be useful tools in molecular biology research, as they provide insight into the biological pathways and cellular processes in which TMEM182 is involved. By selectively inhibiting the activity of TMEM182, researchers can better understand the protein's role in regulating various cellular functions, such as signaling pathways, protein transport, or membrane dynamics. These inhibitors can be studied in different experimental models to explore the consequences of TMEM182 inhibition on cellular processes, which can include changes in protein-protein interactions, alterations in membrane permeability, or shifts in intracellular signaling. Understanding the biochemical properties and molecular interactions of TMEM182 inhibitors can contribute to advancing knowledge in cellular biology and biochemistry.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$182.00
$693.00
88
(1)

A ROCK inhibitor, potentially affecting cytoskeletal dynamics and membrane-associated proteins like TMEM182.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

An mTOR inhibitor, possibly impacting signaling pathways related to TMEM182 function.

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$30.00
$52.00
$122.00
$367.00
25
(3)

An inhibitor of protein transport from the endoplasmic reticulum to the Golgi, affecting membrane protein trafficking.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

A PI3K inhibitor, could influence signaling pathways involving TMEM182.

Cyclosporin A

59865-13-3sc-3503
sc-3503-CW
sc-3503A
sc-3503B
sc-3503C
sc-3503D
100 mg
100 mg
500 mg
10 g
25 g
100 g
$62.00
$90.00
$299.00
$475.00
$1015.00
$2099.00
69
(5)

An immunosuppressant that inhibits calcineurin, potentially affecting signaling pathways linked to TMEM182.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

A PI3K inhibitor that could impact TMEM182-related pathways.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

A specific inhibitor of MEK, which may indirectly influence TMEM182 activity.

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$150.00
$388.00
113
(4)

A non-selective protein kinase inhibitor, potentially affecting TMEM182-related signaling.

Chlorpromazine

50-53-3sc-357313
sc-357313A
5 g
25 g
$60.00
$108.00
21
(1)

A psychotropic agent affecting various neurotransmitters, also influences membrane protein trafficking.

Tunicamycin

11089-65-9sc-3506A
sc-3506
5 mg
10 mg
$169.00
$299.00
66
(3)

An inhibitor of N-linked glycosylation, affecting the maturation and trafficking of membrane proteins like TMEM182.