TMEM167B Activators
TMEM167B Activators constitute a specific category of chemical compounds that have garnered attention in the field of molecular biology and cellular research. These activators are designed to modulate the activity of the TMEM167B gene, with TMEM167B referring to Transmembrane Protein 167B. This gene is a protein-coding element found in humans and is associated with cellular processes related to membrane transport and homeostasis. TMEM167B Activators represent a group of molecules engineered to enhance or stimulate the expression and function of the TMEM167B gene, ultimately leading to increased activity of the associated protein.
The mechanism by which TMEM167B Activators exert their effects typically involves their interaction with specific regulatory elements within the TMEM167B gene, such as promoter regions or enhancer sequences. These interactions facilitate the upregulation of gene transcription, resulting in heightened synthesis of the TMEM167B protein. Researchers are actively exploring the precise role of TMEM167B in cellular processes, particularly its involvement in membrane transport, ion channels, or cellular compartmentalization. As our understanding of TMEM167B activation continues to evolve, the development and refinement of TMEM167B Activators hold promise for advancing our comprehension of membrane biology, intracellular trafficking, and the broader implications of TMEM167B in cellular functionality and molecular mechanisms, potentially uncovering novel aspects of membrane dynamics and cellular homeostasis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid can modulate gene expression during differentiation and development, potentially affecting TMEM167B expression in relevant cell types. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
By elevating cAMP levels, forskolin may influence TMEM167B expression through cAMP-responsive transcription factors in cells responsive to cAMP signaling. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Vitamin D3, via its receptor, might impact TMEM167B expression in cells involved in immune responses, bone metabolism, or calcium homeostasis. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
As an inducer of ER stress, tunicamycin could upregulate TMEM167B as part of the unfolded protein response in cells experiencing protein folding stress. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 18 | |
This histone deacetylase inhibitor may enhance TMEM167B expression by increasing chromatin accessibility and facilitating gene transcription. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
This green tea polyphenol might modulate cellular signaling pathways, potentially affecting TMEM167B expression as part of its anti-inflammatory and antioxidative effects. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin's anti-inflammatory properties might lead to the upregulation of TMEM167B, possibly in pathways related to cellular stress responses or inflammation. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
As a sirtuin activator, resveratrol could influence TMEM167B expression as part of its effects on cellular aging, stress resistance, or metabolic regulation. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
This synthetic glucocorticoid might affect TMEM167B expression in the context of immune modulation or stress response due to its broad regulatory effects. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
As a ribonucleotide reductase inhibitor, hydroxyurea might induce TMEM167B expression as part of cellular responses to DNA damage or replication stress. | ||||||