TMEM102 Inhibitors
TMEM102 inhibitors such as Wortmannin and Genistein, target critical intracellular signaling enzymes like PI3K and tyrosine kinases, respectively. These enzymes play a crucial role in various cellular functions, including those that may govern the expression and activity of transmembrane proteins like TMEM102. Inhibition of these pathways by the chemicals can lead to changes in transmembrane protein dynamics, potentially altering the activity or expression of TMEM102.
Other chemicals, like Brefeldin A and Tunicamycin, specifically target the cellular processes involved in the maturation and trafficking of transmembrane proteins. By inhibiting protein transport and glycosylation, they can cause mislocalization or degradation of proteins, affecting the functional capacity of TMEM102. Furthermore, compounds that disrupt ion homeostasis and calcium signaling, such as Monensin and Xestospongin C, can cause profound effects on the regulation and activity of transmembrane proteins. These alterations in cellular signaling and homeostasis can modulate the function or expression of TMEM102 by creating a cellular environment that is unfavorable for its normal operation.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
A PI3K inhibitor that can disrupt the PI3K/AKT pathway, potentially affecting the activity or expression of TMEM102. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Disrupts protein transport within the Golgi apparatus, which can affect the trafficking and localization of TMEM102. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
Inhibits the GTPase dynamin, affecting endocytosis and membrane cycling of proteins such as TMEM102. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A tyrosine kinase inhibitor that can alter cellular signaling, potentially modifying the function of TMEM102. | ||||||
NF449 | 627034-85-9 | sc-478179 sc-478179A sc-478179B | 10 mg 25 mg 100 mg | $203.00 $469.00 $1509.00 | 1 | |
A Gs-alpha subunit-specific antagonist which can modulate G-protein coupled receptor signaling, potentially affecting pathways involving TMEM102. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $105.00 $299.00 $474.00 | 15 | |
A PKC inhibitor that can change PKC-mediated processes, possibly influencing TMEM102 activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An MEK inhibitor which can alter the MAPK/ERK pathway, potentially affecting TMEM102's role within the cell. | ||||||
Xestospongin C | 88903-69-9 | sc-201505 | 50 µg | $510.00 | 14 | |
An IP3 receptor antagonist that can influence calcium signaling, potentially impacting TMEM102 regulation. | ||||||
2-APB | 524-95-8 | sc-201487 sc-201487A | 20 mg 100 mg | $28.00 $53.00 | 37 | |
An IP3 receptor inhibitor that affects calcium signaling, which can impact the activity of TMEM102. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Inhibits N-linked glycosylation, potentially affecting the folding and stability of TMEM102. | ||||||