Date published: 2026-5-30

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TMC5 Activators

The chemical class of TMC5 activators encompasses a diverse group of compounds found in various natural sources such as fruits, vegetables, and herbs. These activators target intracellular signaling pathways involved in inflammation, oxidative stress, immune regulation, and cellular homeostasis, ultimately leading to the activation of TMC5. Compounds like quercetin, sulforaphane, and diosgenin exert their activatory effects by modulating pathways associated with immune response and cellular homeostasis. Ursolic acid and epigallocatechin gallate (EGCG) activate TMC5 by influencing antioxidant defense mechanisms and cellular stress responses.

Moreover, betulinic acid, andrographolide, and celastrol activate TMC5 through their modulation of signaling pathways related to inflammation and immune regulation. Compounds such as curcumin, resveratrol, and luteolin activate TMC5 by targeting pathways associated with inflammation, oxidative stress, and immune response. Guggulsterone, another activator, influences cellular pathways involved in immune modulation and inflammatory response. Collectively, these TMC5 activators represent a promising class of compounds that can be harnessed for their benefits in modulating cellular processes associated with inflammation and immune dysfunction.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin is a flavonoid compound found in various fruits and vegetables that can activate TMC5 by modulating intracellular signaling pathways involved in its regulation.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

Sulforaphane is a naturally occurring compound present in cruciferous vegetables that can activate TMC5 by influencing cellular pathways related to oxidative stress and inflammation.

Diosgenin

512-04-9sc-205652
sc-205652B
sc-205652A
5 g
25 g
100 g
$47.00
$131.00
$517.00
4
(1)

Diosgenin, a steroidal sapogenin found in certain plants, can activate TMC5 by modulating signaling pathways associated with immune response and cellular homeostasis.

Ursolic Acid

77-52-1sc-200383
sc-200383A
50 mg
250 mg
$56.00
$180.00
8
(1)

Ursolic acid, a pentacyclic triterpenoid present in various fruits and herbs, can activate TMC5 by regulating cellular processes involved in inflammation and immune modulation.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

Epigallocatechin gallate (EGCG), a catechin found in green tea, can activate TMC5 by modulating signaling pathways related to antioxidant defense and cellular stress response.

Betulinic Acid

472-15-1sc-200132
sc-200132A
25 mg
100 mg
$117.00
$344.00
3
(1)

Betulinic acid, a triterpenoid compound derived from birch bark, can activate TMC5 by influencing intracellular pathways associated with immune regulation and inflammatory response.

Andrographolide

5508-58-7sc-205594
sc-205594A
50 mg
100 mg
$15.00
$40.00
7
(1)

Andrographolide, a diterpenoid lactone extracted from Andrographis paniculata, can activate TMC5 by modulating signaling pathways involved in inflammation and immune modulation.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin is a polyphenolic compound derived from turmeric that can activate TMC5 by modulating intracellular pathways related to inflammation, oxidative stress, and immune response.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol is a stilbenoid compound found in grapes and berries that can activate TMC5 by modulating cellular pathways associated with inflammation and oxidative stress.

Luteolin

491-70-3sc-203119
sc-203119A
sc-203119B
sc-203119C
sc-203119D
5 mg
50 mg
500 mg
5 g
500 g
$27.00
$51.00
$101.00
$153.00
$1925.00
40
(1)

Luteolin is a flavonoid compound found in various plants that can activate TMC5 by modulating signaling pathways involved in immune regulation and inflammatory response.