Tim8B activators pivot around modulating mitochondrial dynamics and processes. Many of the listed chemicals operate by directly influencing mitochondrial function, suggesting indirect pathways through which Tim8B's activity can be modulated. For instance, FCCP, an uncoupler of oxidative phosphorylation, generates a cellular environment where mitochondrial protein import and assembly might be enhanced, indirectly influencing Tim8B. Similarly, Rotenone and Antimycin A, by inhibiting specific complexes in the electron transport chain, induce mitochondrial stress responses that can affect proteins like Tim8B.
MitoQ, a targeted antioxidant, along with Resveratrol and Alpha-lipoic acid, emphasizes the importance of redox balance and mitochondrial health in influencing Tim8B's function. Coenzyme Q10 and NAD+, essential components of the electron transport chain and cellular metabolism respectively, underscore the role of general mitochondrial function in Tim8B's activity. Additionally, molecules like Rapamycin and DCA, which significantly impact broader cellular signaling and metabolic pathways respectively, hint at the potential cascading effects on mitochondrial proteins, including Tim8B.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
FCCP | 370-86-5 | sc-203578 sc-203578A | 10 mg 50 mg | $92.00 $348.00 | 46 | |
A protonophore and uncoupler of oxidative phosphorylation in mitochondria, which can indirectly stimulate Tim8B by affecting mitochondrial dynamics. | ||||||
Mito-Q | 444890-41-9 | sc-507441 | 5 mg | $284.00 | ||
Targets the mitochondria and can modulate mitochondrial dynamics, potentially influencing Tim8B. | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $254.00 | 41 | |
An inhibitor of mitochondrial electron transport chain complex I. By affecting mitochondrial function, it may indirectly influence Tim8B activity. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $146.00 $12250.00 | 18 | |
Inhibits ATP synthase and impacts mitochondrial dynamics, which might modulate Tim8B activity. | ||||||
Dichloroacetic acid | 79-43-6 | sc-214877 sc-214877A | 25 g 100 g | $60.00 $125.00 | 5 | |
Stimulates mitochondrial activity by inhibiting pyruvate dehydrogenase kinase, potentially affecting Tim8B indirectly. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $54.00 $62.00 $1642.00 $4600.00 | 51 | |
Inhibitor of electron transport chain complex III, which can affect mitochondrial dynamics and potentially Tim8B. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor known to influence mitochondrial dynamics and function, potentially affecting Tim8B. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Known to influence mitochondrial biogenesis and dynamics, which can indirectly modulate Tim8B. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
A mitochondrial cofactor that can affect mitochondrial function and potentially influence Tim8B. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $70.00 $180.00 | 1 | |
Plays a role in the mitochondrial electron transport chain. By modulating this, it might influence Tim8B. | ||||||