TGase6 Activators
Transglutaminase 6 (TGase6) is an enzyme involved in posttranslational modification of proteins through the formation of ε-(γ-glutamyl) lysine isopeptide bonds. TGase6 Activators represent a class of chemicals that can influence the function of TGase6 indirectly. These compounds exert their effects through their influence on related cellular processes such as endocytosis, membrane trafficking, and cellular signaling.
Chemicals such as Retinoic acid, DTT, Calcium chloride, GTP, Forskolin, Ionomycin, Thapsigargin, PMA, Okadaic acid, Calyculin A, Tautomycetin, and EGF can potentially influence TGase6 function through their effects on these processes. The effects of these chemicals on TGase6 function are context-dependent and may vary based on the cellular environment and other biochemical parameters.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid can influence gene expression and protein modification processes, potentially affecting TGase6 activity. | ||||||
Calcium chloride anhydrous | 10043-52-4 | sc-207392 sc-207392A | 100 g 500 g | $66.00 $262.00 | 1 | |
Calcium ions can stimulate the activity of transglutaminases, including TGase6. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylyl cyclase, increasing intracellular cAMP levels. This can indirectly affect TGase6 by modifying cellular signaling pathways. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $96.00 $264.00 | 2 | |
Ionomycin is a calcium ionophore that can indirectly influence TGase6 by triggering calcium-dependent signaling pathways. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin is a non-competitive inhibitor of the sarco-/endoplasmic reticulum Ca2+ ATPase (SERCA) and can indirectly influence TGase6 by modifying intracellular calcium levels. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a potent activator of Protein Kinase C (PKC) that can indirectly influence TGase6 by modulating the activity of other kinases. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Okadaic acid is a potent inhibitor of protein phosphatases PP1 and PP2A, and can indirectly influence TGase6 by affecting cellular phosphorylation states. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $163.00 $800.00 | 59 | |
Calyculin A is a potent inhibitor of protein phosphatases PP1 and PP2A, and can indirectly influence TGase6 by affecting cellular phosphorylation states. | ||||||