Texas Red Sulfonyl Chloride Activators
Texas Red Sulfonyl Chloride, although primarily a fluorescent label, offers unique insights into VEGFR2 activation. When conjugated with VEGFR2 ligands, it enables the detailed visualization of ligand-receptor interactions. This visualization is critical for understanding the activation mechanism of VEGFR2, as it undergoes conformational changes upon ligand binding. These changes are pivotal for the initiation of downstream signaling cascades that lead to endothelial cell proliferation and migration, which are fundamental processes in angiogenesis. The ability to observe these interactions in real-time provides an unparalleled view of VEGFR2 activation, allowing for the study of its role in physiological and pathological angiogenesis.
In summary, VEGFR2 activation is a complex process that is crucial for vascular development and repair. Texas Red Sulfonyl Chloride, though not a direct activator, plays a significant role in elucidating the activation mechanisms of VEGFR2. By enabling the real-time observation of ligand-receptor interactions, it aids in the understanding of how VEGFR2 transmits signals that drive key endothelial functions. This understanding is essential for developing strategies to modulate VEGFR2 activity in various contexts, such as promoting angiogenesis in wound healing or inhibiting it in tumor growth. Thus, the study of VEGFR2 activation, aided by compounds like Texas Red Sulfonyl Chloride, remains a pivotal area of research in vascular biology.
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Elevates intracellular cAMP levels, enhancing the fluorescence intensity of Texas Red Sulfonyl Chloride by promoting a favorable intracellular environment for its fluorescence activity. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates protein kinase C (PKC), indirectly increasing the fluorescence of Texas Red Sulfonyl Chloride by modulating intracellular signaling pathways. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Increases intracellular calcium levels, potentially enhancing the fluorescence of Texas Red Sulfonyl Chloride through calcium-dependent signaling pathways. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A calcium ionophore that elevates intracellular calcium levels, potentially enhancing the fluorescence of Texas Red Sulfonyl Chloride by influencing calcium-mediated intracellular processes. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
Engages in lipid signaling pathways that could indirectly enhance the fluorescence intensity of Texas Red Sulfonyl Chloride by altering lipid dynamics within cells. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that might enhance Texas Red Sulfonyl Chloride fluorescence by altering PI3K/Akt signaling pathways. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
A MEK inhibitor that could enhance the fluorescence of Texas Red Sulfonyl Chloride by modulating the MAPK/ERK pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Inhibits p38 MAPK, which might indirectly increase the fluorescence of Texas Red Sulfonyl Chloride by altering cellular signaling pathways. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
A tyrosine kinase inhibitor that can potentially enhance the fluorescence of Texas Red Sulfonyl Chloride by affecting tyrosine kinase signaling pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A PI3K inhibitor that could indirectly enhance the fluorescence of Texas Red Sulfonyl Chloride by modulating PI3K/Akt signaling pathways. | ||||||