TEX10 Activators
TEX10 activators are a diverse group of chemical compounds that indirectly enhance the functional activity of TEX10. These compounds work by increasing the levels of cAMP in the cell, a second messenger that is crucial for the activation of TEX10. The activators can be broadly classified into three groups based on their mechanism of action. Firstly, Forskolin, a potent adenylyl cyclase activator, boosts the production of cAMP, which indirectly leads to the activation of TEX10. Secondly, the phosphodiesterase inhibitors, IBMX, Rolipram, and Papaverine, work by inhibiting the degradation of cAMP, thereby maintaining high intracellular cAMP levels that eventually lead to the activation of TEX10.
Lastly, the receptor agonists, including Epinephrine, Isoproterenol, Dopamine, Histamine, Salbutamol, PGE2, Glucagon, and Terbutaline, bind to their respective receptors, triggering a series of cellular events that result in increased cAMP levels and ultimately lead to the activation of TEX10. By increasing the level of intracellular cAMP, these compounds indirectly lead to the activation of TEX10.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is a potent activator of adenylyl cyclase, which catalyzes the conversion of ATP to cAMP. cAMP is a second messenger, crucial in the signaling pathways that lead to the activation of TEX10. By increasing the production of cAMP, Forskolin indirectly enhances the functional activity of TEX10. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX is a non-selective phosphodiesterase inhibitor, which helps maintain high levels of cAMP by preventing its breakdown. Elevated cAMP levels can lead to the activation of TEX10, thereby enhancing its functional activity. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram is a selective phosphodiesterase-4 inhibitor. By inhibiting PDE4, it increases cAMP levels, indirectly leading to TEX10 activation and thus enhancing its functional activity. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine activates adrenergic receptors, leading to increased cAMP levels. The elevated cAMP levels then induce the activation of TEX10, enhancing its functional activity. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol is a non-selective beta adrenergic receptor agonist which increases cAMP levels, indirectly leading to TEX10 activation and enhanced functional activity. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
Dopamine activates D1-like dopamine receptors, resulting in increased cAMP levels. The subsequent rise in cAMP levels activates TEX10, enhancing its functional activity. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $94.00 $283.00 $988.00 | 7 | |
Histamine acts on H2 receptors, increasing the levels of cAMP. The increased cAMP levels then lead to the activation of TEX10, enhancing its functional activity. | ||||||
Salbutamol | 18559-94-9 | sc-253527 sc-253527A | 25 mg 50 mg | $94.00 $141.00 | ||
Salbutamol is a selective beta-2 adrenergic receptor agonist that increases cAMP levels. The rise in cAMP levels activates TEX10, enhancing its functional activity. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
Prostaglandin E2 (PGE2) acts on EP receptors, increasing cAMP levels. The subsequent rise in cAMP levels leads to the activation of TEX10, enhancing its functional activity. | ||||||
Papaverine | 58-74-2 | sc-279951 sc-279951A sc-279951B | 10 mg 50 mg 100 mg | $153.00 $265.00 $459.00 | ||
Papaverine is a non-selective phosphodiesterase inhibitor that maintains high cAMP levels by inhibiting its breakdown. The elevated cAMP levels will then activate TEX10, enhancing its functional activity. | ||||||