Adenosine deaminase domain containing 1 (ADAD1) is a protein encoded by the ADAD1 gene in humans. While the full extent of its function is not completely understood, it is known to belong to the adenosine deaminase (ADA) family of enzymes, which play a critical role in purine metabolism. These enzymes catalyze the deamination of adenosine, converting it to inosine, and are integral in the turnover of nucleic acids in tissues.
ADAD1 is thought to have a specialized function due to its domain structure that is distinct from other ADA enzymes, suggesting a unique role in cellular metabolism. Its expression and activity are likely important for maintaining the balance of adenosine and deoxyadenosine levels in cells, which is crucial for numerous physiological processes, including signal transduction, metabolic regulation, and possibly neurotransmission.The precise mechanisms of ADAD1's function and regulation, its tissue distribution, and its physiological and pathological roles remain areas of active research. Understanding ADAD1's activity could provide insights into various biological processes and reveal novel targets for diseases where purine metabolism is disrupted
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
May regulate gene expression by acting as a ligand for nuclear receptors. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylyl cyclase, potentially increasing cAMP and PKA activity, which can modulate transcription factors. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Inhibits histone deacetylase, leading to a more open chromatin structure and potential gene activation. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, which can lead to demethylation and activation of some genes. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Inhibits histone deacetylase, potentially increasing gene expression by affecting chromatin structure. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenol that may modulate gene expression through epigenetic mechanisms. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
A glucocorticoid that can regulate gene expression by acting on glucocorticoid response elements. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
May influence glycogen synthase kinase 3 (GSK-3) activity, affecting Wnt signaling and gene expression. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
A hormone that can bind to estrogen receptors and affect gene transcription. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C, which can lead to altered transcription factor activity and gene expression. | ||||||