Tas2r102 Inhibitors
Tas2r102 inhibitors are a class of chemical compounds that specifically target and inhibit the activity of the Tas2r102 receptor, which is part of the TAS2R family of bitter taste receptors. Tas2r102 is a G-protein-coupled receptor (GPCR) primarily located in the taste receptor cells of the tongue, where it is responsible for detecting bitter compounds. When bitter molecules bind to Tas2r102, the receptor activates intracellular signaling cascades that ultimately lead to the perception of bitterness. Inhibition of Tas2r102 disrupts this process by blocking the receptor's ability to bind with bitter ligands, thus preventing the initiation of the signaling pathways associated with bitter taste perception.
Studying Tas2r102 inhibitors provides important insights into the molecular basis of taste perception, particularly in understanding how bitter compounds are recognized and processed by the sensory system. These inhibitors allow researchers to explore the specificity of Tas2r102 for various bitter molecules and to better understand how this receptor contributes to the overall detection of bitterness in conjunction with other TAS2R receptors. By blocking Tas2r102 activity, scientists can also investigate the structural and functional dynamics of G-protein-coupled receptors in taste transduction and explore how the inhibition of this receptor affects taste signal transmission to the brain. Additionally, Tas2r102 inhibitors are useful for mapping the role of specific taste receptors in taste preferences and aversions, enhancing the broader understanding of sensory biology and the complexity of taste perception at the molecular level. Through these studies, researchers can gain a more comprehensive view of the interactions between taste receptors and bitter compounds in sensory cells.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol may inhibit taste receptor type 2 member 102 expression by modulating sirtuin activity, leading to changes in chromatin structure that could affect the transcription of the TAS2R102 gene. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin may inhibit taste receptor type 2 member 102 expression by modulating various signaling pathways involved in gene expression regulation, thus affecting the transcription of the TAS2R102 gene. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Epigallocatechin gallate may inhibit taste receptor type 2 member 102 expression by modulating transcription factors or coactivators involved in the regulation of TAS2R102 gene expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein may inhibit taste receptor type 2 member 102 expression by interfering with estrogen receptor signaling, which could modulate downstream transcriptional regulation of the TAS2R102 gene. | ||||||
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $99.00 $216.00 $510.00 | 11 | |
Kaempferol may inhibit taste receptor type 2 member 102 expression by modulating transcription factors or coactivators involved in the regulation of TAS2R102 gene expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin may inhibit taste receptor type 2 member 102 expression by modulating transcription factors or coactivators involved in the regulation of TAS2R102 gene expression. | ||||||
Naringenin | 480-41-1 | sc-219338 | 25 g | $245.00 | 11 | |
Naringenin may inhibit taste receptor type 2 member 102 expression by modulating transcription factors or coactivators involved in the regulation of TAS2R102 gene expression. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $33.00 $214.00 $734.00 $1151.00 $2348.00 $3127.00 $5208.00 | 22 | |
Apigenin may inhibit taste receptor type 2 member 102 expression by modulating transcription factors or coactivators involved in the regulation of TAS2R102 gene expression. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Luteolin may inhibit taste receptor type 2 member 102 expression by modulating transcription factors or coactivators involved in the regulation of TAS2R102 gene expression. | ||||||
Fisetin | 528-48-3 | sc-276440 sc-276440A sc-276440B sc-276440C sc-276440D | 50 mg 100 mg 500 mg 1 g 100 g | $52.00 $79.00 $104.00 $156.00 $2913.00 | 7 | |
Fisetin may inhibit taste receptor type 2 member 102 expression by modulating transcription factors or coactivators involved in the regulation of TAS2R102 gene expression. | ||||||