T2R37 Inhibitors
The protein described as "taste 2 receptor member 37 pseudogene" refers to a sequence in the genome identified as a pseudogene related to the family of taste 2 receptors, which are part of the bitter taste receptor family. Pseudogenes arise from the remnants of once-functional genes that, through evolutionary processes such as mutation, deletion, or insertion, have lost their ability to encode a functional protein.Taste 2 receptor member 37 pseudogene, which may be designated as TAS2R37P or a variant thereof, is a genetic element that bears significant sequence homology to its parent gene TAS2R37, a functional bitter taste receptor. However, due to its pseudogene status, it does not produce an active protein product capable of contributing to taste perception. The presence of pseudogenes in the genome is common, and they are often considered to be genetic "fossils" that provide insight into the evolutionary history of organisms.
While pseudogenes are typically nonfunctional, they sometimes play roles in gene regulation or act as a genomic reservoir that may give rise to new genes or functions through the process of gene duplication and divergence. In some cases, pseudogenes have been found to express noncoding RNAs, which can have regulatory effects on their functional counterparts or other genes.The taste 2 receptor member 37 pseudogene's existence reflects the complex and dynamic nature of the genome, where gene duplication events and functional diversification contribute to the adaptability of organisms. In the context of taste receptors, the large family of bitter taste receptors, including both functional genes and pseudogenes, illustrates the evolutionary pressure to detect a wide range of bitter substances, which can signal the presence of toxins in food sources. Understanding pseudogenes like TAS2R37P helps to map the evolutionary landscape of taste and the genetic underpinnings of chemosensory perception.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
Ellagic acid might inhibit the expression of taste 2 receptor member 37 pseudogene by interfering with transcription factors and downregulating gene expression. Its antioxidant properties could contribute to reducing the expression of this pseudogene. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin's modulation of signaling pathways and inhibition of transcription factors might result in the downregulation of taste 2 receptor member 37 pseudogene expression. Additionally, its antioxidant properties could play a role in reducing the expression of this pseudogene. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane may inhibit the expression of taste 2 receptor member 37 pseudogene by modulating gene expression through epigenetic mechanisms and inhibiting transcription factors. Its antioxidant properties could also impact signaling pathways involved in the expression of this pseudogene. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein's ability to modulate transcription factors and signaling pathways involved in gene expression could result in the downregulation of taste 2 receptor member 37 pseudogene. Additionally, its anti-inflammatory properties may influence the expression of this pseudogene. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Luteolin's modulation of gene expression through various signaling pathways may inhibit the expression of taste 2 receptor member 37 pseudogene. Its anti-inflammatory effects might also contribute to reducing the expression of this pseudogene by impacting relevant pathways. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine's interference with transcription factors and modulation of gene expression may lead to the inhibition of taste 2 receptor member 37 pseudogene expression. Its anti-inflammatory effects might also impact relevant signaling pathways involved in the expression of this pseudogene. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin may inhibit the expression of taste 2 receptor member 37 pseudogene by interfering with transcription factors and downregulating gene expression. Its anti-inflammatory properties might also play a role in reducing the expression of this pseudogene. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol's ability to modulate transcription factors and inhibit gene expression could lead to the downregulation of taste 2 receptor member 37 pseudogene. Its antioxidant properties may also contribute to reducing the expression of this pseudogene. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG can potentially inhibit the expression of taste 2 receptor member 37 pseudogene by modulating various signaling pathways involved in gene expression regulation. Its antioxidant properties may also contribute to reducing the expression of this pseudogene. | ||||||
Baicalein | 491-67-8 | sc-200494 sc-200494A sc-200494B sc-200494C | 10 mg 100 mg 500 mg 1 g | $32.00 $42.00 $162.00 $292.00 | 12 | |
Baicalein can potentially inhibit the expression of taste 2 receptor member 37 pseudogene by interfering with transcription factors and modulating gene expression. Its anti-inflammatory effects may also influence signaling pathways involved in the expression of this pseudogene. | ||||||