Sup35 Activators
The chemical class Sup35 Activators includes compounds that indirectly influence Sup35 through various pathways, particularly those involved in protein folding, aggregation, and cellular stress responses. Chemicals like Guanidine Hydrochloride and Dithiothreitol (DTT) directly impact protein folding and aggregation, which are key aspects of Sup35's prion-like behavior. Lithium Chloride, with its effect on glycogen synthase kinase-3, and antioxidants like Sodium Selenite and Curcumin could modulate the aggregation dynamics of Sup35. EGCG, a polyphenol, along with Curcumin, has properties that affect amyloid formation, thereby potentially influencing Sup35 aggregation.
Compounds like Methionine and Tunicamycin indirectly affect Sup35 by modulating translation fidelity and inducing endoplasmic reticulum stress, respectively. Phenazine Methosulfate, inducing oxidative stress, and Chlorpromazine, affecting cellular signaling, might also impact Sup35's function and aggregation state. Congo Red and Quinacrine, known for their interaction with amyloid aggregates, could potentially influence the aggregation behavior of Sup35.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Guanidine Hydrochloride | 50-01-1 | sc-202637 sc-202637A sc-202637B | 100 g 1 kg 25 kg | $61.00 $310.00 $1975.00 | 1 | |
Disrupts prion aggregates; may influence Sup35 aggregation and its function in translation. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Affects glycogen synthase kinase-3 activity, potentially influencing Sup35 aggregation dynamics. | ||||||
Sodium selenite | 10102-18-8 | sc-253595 sc-253595B sc-253595C sc-253595A | 5 g 500 g 1 kg 100 g | $49.00 $183.00 $316.00 $98.00 | 3 | |
An antioxidant that can modulate oxidative stress, possibly affecting Sup35 aggregation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Known for anti-amyloid properties; may influence Sup35 amyloid formation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenol with anti-amyloid activity, potentially affecting Sup35 aggregation. | ||||||
L-Methionine | 63-68-3 | sc-394076 sc-394076A sc-394076B sc-394076C sc-394076D sc-394076E | 25 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $37.00 $57.00 $151.00 $577.00 $1103.00 | ||
An amino acid that can modulate translation fidelity, potentially influencing Sup35 activity. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Inhibits N-linked glycosylation, causing ER stress, potentially impacting Sup35 function. | ||||||
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $61.00 $110.00 | 21 | |
Modulates cellular signaling pathways; might influence protein aggregation and Sup35 activity. | ||||||
Congo Red | 573-58-0 | sc-359843 sc-359843A sc-359843B sc-359843C | 25 g 100 g 250 g 1 kg | $37.00 $89.00 $182.00 $505.00 | 4 | |
An amyloid-binding dye, can affect amyloid aggregation, potentially impacting Sup35. | ||||||
Quinacrine, Dihydrochloride | 69-05-6 | sc-204222 sc-204222B sc-204222A sc-204222C sc-204222D | 100 mg 1 g 5 g 200 g 300 g | $46.00 $57.00 $87.00 $3257.00 $4821.00 | 4 | |
Known to modulate prion aggregation, potentially influencing Sup35 amyloid formation. | ||||||