Congo Red CAS: 573-58-0
MF: C32H22N6O6S2•2Na
MW: 696.7
An amyloidophylic dye that stains β sheet aggregates.

Congo Red (CAS 573-58-0)

Congo Red | CAS 573-58-0 is rated 5.0 out of 5 by 1.
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Alternate Names: C.I.Direct Red 28; Congo Red 4B; Cosmos Red; Cotton Red B; Cotton Red C; Direct Red 28; Direct Red R; Direct Red Y
Application: Congo Red is an amyloidophylic dye that stains β sheet aggregates
CAS Number: 573-58-0
Molecular Weight: 696.7
Molecular Formula: C32H22N6O6S22Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Congo red is an amyloidophylic dye that specifically stains stacked β sheet aggregates. Congo red is useful for staining and visual detection of amyloid deposits. This compound does not bind to non-polymerized amyloid peptide. Congo red inhibits the accumulation of the scrapie-associated, protease-resistant isoform of protein PrP without affecting the metabolism of the normal isoform.

Physical State :
Solid
Solubility :
EtOH or H2O
Storage :
Store at room temperature
Melting Point :
>360° C (lit.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
11313
SMILES :
C1=CC=C2C(=C1)C(=CC(=C2N)N=NC3=CC=C(C=C3)C4=CC=C(C=C4)N=NC5=C(C6=CC=CC=C6C(=C5)S(=O)(=O)[O-])N)S(=O)(=O)[O-].[Na+].[Na+]

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Congo Red (CAS 573-58-0) Product Citations

See how others have used Congo Red (CAS 573-58-0). Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 23405115  He, P. et al. 2013. PLoS ONE. 8: -.

PMID: # 22917926  McCoy, A. et al. 2013. Dis Model Mech. 6: 269-278.

Citations 1 to 2 of 2 total

I'd like to know how pure this is (congo red). The certificate of analysis requires a lot #, but we haven't pruchased any yet. Also, I'd like to know this information for Direct Red 23. Thank you!

Asked by: EileenM
Thank you for your question. We do not offer purity information for this dye. Here is a link to a recent CoA. Please keep in mind that this information is lot specific and the CoA below is a sample CoA for a recent lot and may not be accurate for any lot you have or may receive. http://datasheets.scbt.com/coa/coa.php?sc=sc-359843&lot=H0219
Answered by: Tech Service
Date published: 2019-09-25

i tried to dissolve 30 mg of ECR in 100 mM Tris, 1 mM CaCl2, pH 7.5 but it didn't dissolve well, so what should i do?

Asked by: todeh
Thank you for your question. This chemical is soluble in EtOH or H2O, I have no information regarding Tris or CaCl2 as a solvent. Please contact our European Technical Service team, they would be happy to help you! You can reach them by phone at Toll Free: +49 6221 4503 0, by email at: [email protected] or by live chat directly on our website, www.scbt.com.
Answered by: Tech Service
Date published: 2018-09-27
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Rated 5 out of 5 by from Various publications cite the use of congo red dye Various publications cite the use of congo red dye, as it is an amyloidophylic dye that stains beta sheet aggregates. -SCBT Publication Review
Date published: 2015-03-27
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