Date published: 2025-10-9

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L-Methionine (CAS 63-68-3)

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Alternate Names:
L-MET; L-Lobamine; H-Met-OH
Application:
L-Methionine is an essential amino acid
CAS Number:
63-68-3
Molecular Weight:
149.21
Molecular Formula:
C5H11NO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Methionine is the L-isomer of methionine, an essential amino acid for human development. Methionine is important in many functions, including acting as a hepatoprotectant, an acetominophen poisoning antidote, and a urinary acidifier. It is also a chelating agent for heavy metals.


L-Methionine (CAS 63-68-3) References

  1. L-leucine, L-methionine, and L-phenylalanine share a Na(+)/K (+)-dependent amino acid transporter in shrimp hepatopancreas.  |  Duka, A. and Ahearn, GA. 2013. J Comp Physiol B. 183: 763-71. PMID: 23615795
  2. L-Methionine inhibits growth of human pancreatic cancer cells.  |  Benavides, MA., et al. 2014. Anticancer Drugs. 25: 200-3. PMID: 24126240
  3. Effect of L-Methionine on the Risk of Phosphate Stone Formation.  |  Siener, R., et al. 2016. Urology. 98: 39-43. PMID: 27521063
  4. Enhanced L-methionine production by genetically engineered Escherichia coli through fermentation optimization.  |  Zhou, HY., et al. 2019. 3 Biotech. 9: 96. PMID: 30800607
  5. l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats.  |  Wang, Z., et al. 2019. J Sci Food Agric. 99: 4849-4862. PMID: 31001831
  6. Enhanced production of L-methionine in engineered Escherichia coli with efficient supply of one carbon unit.  |  Tang, XL., et al. 2020. Biotechnol Lett. 42: 429-436. PMID: 31865476
  7. Novel method for l-methionine determination using l-methionine decarboxylase and application of the enzyme for l-homocysteine determination.  |  Okawa, A., et al. 2020. Biosci Biotechnol Biochem. 84: 927-935. PMID: 31959065
  8. Calcium Carbonate Addition Improves L-Methionine Biosynthesis by Metabolically Engineered Escherichia coli W3110-BL.  |  Zhou, HY., et al. 2020. Front Bioeng Biotechnol. 8: 300. PMID: 32426336
  9. Sensing of L-methionine in biological samples through fully 3D-printed electrodes.  |  Kalinke, C., et al. 2021. Anal Chim Acta. 1142: 135-142. PMID: 33280691
  10. Production of l-Methionine from 3-Methylthiopropionaldehyde and O-Acetylhomoserine by Catalysis of the Yeast O-Acetylhomoserine Sulfhydrylase.  |  Wang, H., et al. 2021. J Agric Food Chem. 69: 7932-7937. PMID: 34232654
  11. l-Methionine may modulate the assembly of SARS-CoV-2 by interfering with the mechanism of RNA polymerase.  |  Benavides, MA. 2022. Med Hypotheses. 161: 110798. PMID: 35185264
  12. Increased NADPH Supply Enhances Glycolysis Metabolic Flux and L-methionine Production in Corynebacterium glutamicum.  |  Liu, B., et al. 2022. Foods. 11: PMID: 35407118
  13. L-Methionine supplementation attenuates high-fat fructose diet-induced non-alcoholic steatohepatitis by modulating lipid metabolism, fibrosis, and inflammation in rats.  |  Navik, U., et al. 2022. Food Funct. 13: 4941-4953. PMID: 35437549
  14. L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats.  |  Wang, Z., et al. 2022. Nutr Res Pract. 16: 729-744. PMID: 36467767
  15. High-Level Production of l-Methionine by Dynamic Deregulation of Metabolism with Engineered Nonauxotroph Escherichia coli.  |  Niu, K., et al. 2023. ACS Synth Biol. 12: 492-501. PMID: 36701126

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Methionine, 25 g

sc-394076
25 g
$33.00

L-Methionine, 100 g

sc-394076A
100 g
$36.00

L-Methionine, 250 g

sc-394076B
250 g
$56.00

L-Methionine, 1 kg

sc-394076C
1 kg
$148.00

L-Methionine, 5 kg

sc-394076D
5 kg
$566.00

L-Methionine, 10 kg

sc-394076E
10 kg
$1081.00