SULT1B1 Activators
SULT1B1 activators are compounds that can influence its activity through modulation of related cellular pathways and gene expression. These activators work primarily through the induction of cellular signaling pathways that lead to the transcriptional upregulation of detoxification enzymes. For instance, retinoic acid, through its interaction with nuclear receptors, has the capacity to increase the expression of phase II metabolic enzymes, including potentially SULT1B1.
Moreover, activators such as sulforaphane, diallyl sulfide, and oltipraz, which can trigger the Nrf2 signaling pathway, exemplify how dietary and environmental compounds can enhance the body's detoxification and antioxidant response, including the upregulation of sulfotransferases. Other compounds, including flavonoids like chrysin, and elements such as zinc, selenium, and magnesium, can have more generalized effects on the expression and functional activity of a wide range of enzymes, with potential implications for SULT1B1 activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A metabolite of vitamin A that can regulate gene expression. It can influence the expression of phase II drug-metabolizing enzymes such as sulfotransferases through retinoic acid receptors, possibly leading to increased expression and activity of SULT1B1. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
An antibiotic that acts as a potent inducer of drug-metabolizing enzymes via the pregnane X receptor (PXR), which may lead to upregulation of SULT1B1 activity. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
A compound in cruciferous vegetables that can induce phase II detoxifying enzymes, possibly including sulfotransferases, through the Nrf2 pathway. | ||||||
Diallyl sulfide | 592-88-1 | sc-204718 sc-204718A | 25 g 100 g | $41.00 $104.00 | 3 | |
Found in garlic, it can induce phase II metabolic enzymes, potentially affecting SULT1B1 expression through various signaling pathways including Nrf2. | ||||||
Oltipraz | 64224-21-1 | sc-205777 sc-205777A | 500 mg 1 g | $286.00 $622.00 | ||
An antischistosomal agent that can upregulate phase II detoxification enzymes including sulfotransferases by activation of Nrf2. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A bioactive compound from turmeric that can modulate phase II detoxifying enzyme levels, which may include SULT1B1, via Nrf2 pathway activation. | ||||||
Chrysin | 480-40-0 | sc-204686 | 1 g | $37.00 | 13 | |
A flavonoid that can affect the activity of drug-metabolizing enzymes and may influence sulfotransferase activity through modulation of nuclear receptors. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
An essential trace element that is known to be important for the structure and function of a wide range of enzymes, possibly affecting the activity of SULT1B1. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $61.00 | 1 | |
A trace element that is known to influence the expression and function of various detoxifying enzymes, which could include sulfotransferases. | ||||||