Date published: 2026-4-5

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Stat3 Antibodies

Santa Cruz Biotechnology features a diverse variety of Stat3 monoclonal antibodies for advanced research in cellular signaling and gene regulation. Signal Transducer and Activator of Transcription 3 (Stat3) monoclonal antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Signal Transducer and Activator of Transcription 3 (Stat3) plays a critical role in mediating responses to cytokines and growth factors, influencing processes such as cell growth, survival, and differentiation. Dysregulation of Stat3 is often associated with various cancers and inflammatory diseases, making it a significant target for therapeutic intervention. Understanding the function of Stat3 is essential for elucidating its role in pathophysiological conditions and developing potential treatments. Researchers worldwide utilize Signal Transducer and Activator of Transcription 3 (Stat3) monoclonal antibodies to investigate cellular pathways and molecular mechanisms. Current studies focus on how Stat3 activation patterns influence disease progression and treatment responses. Ongoing research examines Stat3's involvement in immune system regulation and tissue development. Santa Cruz Biotechnology monoclonal antibodies for Signal Transducer and Activator of Transcription 3 (Stat3) support researchers in advancing scientific understanding of disease mechanisms and potential therapeutic approaches.

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Stat3 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Stat3 Antibody (F-2)

sc-8019mouse IgG1 κ50-240 (h)WB, IP, IF, IHC(P), ELISAm, r, h
538
(84)

Stat3 Antibody (285.87)

sc-293151mouse IgG1 λ1-175 (h)WB, IP, ELISAm, r, h
30
(6)

Phospho-Specific Stat3 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-Stat3 Antibody (B-7)

sc-8059mouse IgG2b κTyr 705 (h)WB, IP, IF, IHC(P), FCM, ELISAm, r, h
476
(67)

p-Stat3 Antibody (9E12)

sc-81523mouse IgG1Tyr 705 (h)WB, IP, IFm, r, h and canine
29
(5)

p-Stat3 Antibody (23G5)

sc-56747mouse IgG1Ser 727 (h)WB, IPm, r, h and canine
18
(2)

p-Stat3 Antibody (6D779)

sc-71792mouse IgG1Ser 727 (h)WB, IPm, r, h and canine
11
(3)

p-Stat3 Antibody (pS727.25)

sc-293059mouse IgG1 κSer 727 (h)WB, IP, IFh, r
10
(16)

p-Stat3 Antibody (pS727.49)

sc-136193mouse IgG1 κSer 727 (h)WB, IP, IFm, r, h
10
(4)

Stat3 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Stat3 CRISPR/Cas9 KO Plasmid (h)

sc-400027hGene KnockoutGFP
3
(1)

Stat3 HDR Plasmid (h)

sc-400027-HDRhHomology Directed RepairPuromycin
3
(1)

Stat3 Double Nickase Plasmid (h)

sc-400027-NIChGene KnockoutPuromycin
3
(1)

Stat3 Double Nickase Plasmid (h2)

sc-400027-NIC-2hGene KnockoutPuromycin
3
(1)

Stat3 CRISPR/Cas9 KO Plasmid (m)

sc-423176mGene KnockoutGFP
1
(0)

Stat3 HDR Plasmid (m)

sc-423176-HDRmHomology Directed RepairPuromycin
1
(0)

Stat3 Double Nickase Plasmid (m)

sc-423176-NICmGene KnockoutPuromycin
1
(0)

Stat3 Double Nickase Plasmid (m2)

sc-423176-NIC-2mGene KnockoutPuromycin
1
(0)

Stat3 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Stat3 CRISPR Activation Plasmid (h)

sc-400027-ACThGene ActivationPuro, Blast, Hygro
3
(1)

Stat3 CRISPR Activation Plasmid (h2)

sc-400027-ACT-2hGene ActivationPuro, Blast, Hygro
3
(1)

Stat3 Lentiviral Activation Particles (h)

sc-400027-LAChGene ActivationPuro, Blast, Hygro
3
(1)

Stat3 CRISPR Activation Plasmid (m)

sc-423176-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

Stat3 CRISPR Activation Plasmid (m2)

sc-423176-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

Stat3 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Stat3 siRNA (h)

sc-29493hGene SilencingN/A
218
(1)

Stat3 siRNA (h2)

sc-44275hGene SilencingN/A
5
(0)

Stat3 shRNA Plasmid (h)

sc-29493-SHhGene SilencingPuromycin
218
(1)

Stat3 shRNA Plasmid (h2)

sc-44275-SHhGene SilencingPuromycin
5
(0)

Stat3 shRNA (h) Lentiviral Particles

sc-29493-VhGene SilencingPuromycin
218
(1)

Stat3 shRNA (h2) Lentiviral Particles

sc-44275-VhGene SilencingPuromycin
5
(0)

Stat3 siRNA (m)

sc-29494mGene SilencingN/A
54
(1)

Stat3 shRNA Plasmid (m)

sc-29494-SHmGene SilencingPuromycin
54
(1)

Stat3 shRNA (m) Lentiviral Particles

sc-29494-VmGene SilencingPuromycin
54
(1)

Stat3 siRNA (r)

sc-270027rGene SilencingN/A
27
(0)

Stat3 shRNA Plasmid (r)

sc-270027-SHrGene SilencingPuromycin
27
(0)

Stat3 shRNA (r) Lentiviral Particles

sc-270027-VrGene SilencingPuromycin
27
(0)