p-Stat3 Antibody (pS727.25): sc-293059
- p-Stat3 Antibody (pS727.25) is a mouse monoclonal IgG1 κ, cited in 10 publications, provided at 200 µg/ml
- raised against a short amino acid sequence containing phosphorylated Ser 727 of Stat3 of human origin
- recommended for detection of Ser 727 phosphorylated Stat3 of human and rat origin of human and rat origin by WB, IP and IF; non cross-reactive with Ser 727 phosphorylated Stat3 of mouse origin
- TransCruz reagent for Gel Supershift and ChIP applications (sc-293059 X, 200 µg/0.1 ml)
- m-IgG1 BP-HRP is the preferred secondary detection reagent for p-Stat3 Antibody (pS727.25) for WB applications. This reagent is now offered in a bundle with p-Stat3 Antibody (pS727.25) (see ordering information below).
p-Stat3 Antibody (pS727.25) is a mouse monoclonal IgG1 antibody that detects phosphorylated Stat3 in human and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). p-Stat3 monoclonal antibody (pS727.25) recognizes the phosphorylated form of Stat3 at serine 727, a critical modification that plays a significant role in the regulation of gene expression and cellular responses to various stimuli, including cytokines and growth factors. The phosphorylation of Stat3 at this site is essential for its full transcriptional activity, influencing processes such as cell proliferation, survival, and differentiation. Stat3 is predominantly located in the cytoplasm but translocates to the nucleus upon activation, where Stat3 binds to specific DNA sequences to modulate the expression of target genes involved in immune responses and oncogenesis. The ability of Stat3 to interact with other signaling pathways, including those mediated by Janus kinases (JAKs) and various cytokines, underscores Stat3′s importance in both normal physiological processes and pathological conditions, such as cancer and autoimmune diseases. p-Stat3 monoclonal antibody (pS727.25) is an invaluable tool for researchers investigating the intricate signaling networks that govern cell behavior and the implications of Stat3 activation in disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-Stat3 Antibody (pS727.25) | sc-293059 | 200 µg/ml | $322.00 | |||
p-Stat3 Antibody (pS727.25): m-IgG1 BP-HRP Bundle | sc-550932 | 200 µg Ab; 20 µg BP | $361.00 | |||
p-Stat3 Antibody (pS727.25) X | sc-293059 X | 200 µg/0.1 ml | $322.00 |