STAM2 Inhibitors
STAM2 inhibitors target and inhibit Signal Transducing Adaptor Molecule 2 (STAM2), a protein implicated in intracellular signaling and trafficking pathways. STAM2 is a part of the endosomal sorting complex required for transport (ESCRT) system, playing a pivotal role in the sorting of ubiquitinated cargo proteins for lysosomal degradation. The function of STAM2 in cellular processes, particularly in the regulation of receptor signaling and degradation, makes it a notable target for specific inhibitors. These inhibitors often incorporate functional groups and structural motifs that engage with key regions of STAM2, such as its SH3 domain or ubiquitin-interacting motifs. These inhibitors have complex molecular frameworks that can mimic or compete with the natural substrates or binding partners of STAM2, thereby inhibiting its function.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A metabolite of vitamin A that regulates gene expression and may downregulate STAM2 via retinoic acid receptor-mediated pathways. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A polyphenol found in green tea that may modulate gene expression through epigenetic changes, potentially altering STAM2 levels. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
An isoflavone that acts as an epigenetic modulator, potentially influencing the expression of proteins like STAM2. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A compound from turmeric with potential effects on transcription factors and gene expression, which may include STAM2. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
A compound in cruciferous vegetables that may affect epigenetic regulation, potentially altering STAM2 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Found in grapes, this polyphenol may influence gene expression through sirtuin activation, possibly affecting STAM2. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Affects glycogen synthase kinase 3 (GSK-3) activity, which could lead to changes in transcription factor activity and STAM2 expression. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
An antimetabolite that can incorporate into RNA and DNA, potentially disrupting gene expression including that of STAM2. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that could disrupt pathways upstream, possibly affecting STAM2 expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that may have broad effects on protein synthesis and gene expression, including STAM2. | ||||||