Ssn6 Inhibitors
Ssn6 inhibitors are primarily centered on influencing the activity of the Tup1-Ssn6 co-repressor complex in yeast. As a critical component of this complex, Ssn6 plays a role in the regulation of various genes. Direct inhibition of Ssn6 is not well-documented, leading us to focus on compounds that modulate related pathways or processes. Notably, histone deacetylase inhibitors like Trichostatin A and Sodium butyrate can modify the chromatin structure, impacting the binding and activity of the Tup1-Ssn6 complex.
Furthermore, the DNA methyltransferase inhibitor, 5-Azacytidine, can influence gene expression, providing an indirect avenue to modulate Ssn6 functions. Yeast metabolism and signaling are intricate and interconnected. Compounds such as Miconazole and Fluconazole, which affect ergosterol synthesis, may indirectly affect processes regulated by Tup1-Ssn6. Proteasome and autophagy inhibitors, like MG-132 and 3-Methyladenine respectively, can alter cellular homeostasis and protein interactions, thereby offering influence over the Tup1-Ssn6 complex.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Histone deacetylase inhibitor that can modify chromatin structure and potentially impact Tup1-Ssn6 complex binding. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Another histone deacetylase inhibitor that might affect Tup1-Ssn6 activity by altering chromatin accessibility. | ||||||
Miconazole | 22916-47-8 | sc-204806 sc-204806A | 1 g 5 g | $66.00 $160.00 | 2 | |
Antifungal that affects ergosterol synthesis and can influence multiple pathways in yeast, possibly affecting Tup1-Ssn6 related processes. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Proteasome inhibitor that can stabilize various proteins, potentially altering interactions with the Tup1-Ssn6 complex. | ||||||
Autophagy Inhibitor, 3-MA | 5142-23-4 | sc-205596 sc-205596A | 50 mg 500 mg | $65.00 $261.00 | 113 | |
Autophagy inhibitor that might indirectly influence Tup1-Ssn6 functionality by altering cellular homeostasis. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Targets TOR signaling in yeast and might affect processes regulated by the Tup1-Ssn6 complex. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Protein synthesis inhibitor that could impact protein levels and potentially influence Tup1-Ssn6 functions. | ||||||
Cerulenin (synthetic) | 17397-89-6 | sc-200827 sc-200827A sc-200827B | 5 mg 10 mg 50 mg | $161.00 $312.00 $1210.00 | 9 | |
Fatty acid synthase inhibitor which may influence yeast metabolism, indirectly impacting Tup1-Ssn6 activity. | ||||||
Amphotericin B | 1397-89-3 | sc-202462 sc-202462A sc-202462B | 100 mg 500 mg 1 g | $70.00 $142.00 $223.00 | 10 | |
Affects yeast membrane function and might indirectly influence signaling pathways related to Tup1-Ssn6. | ||||||
Fluconazole | 86386-73-4 | sc-205698 sc-205698A | 500 mg 1 g | $54.00 $84.00 | 14 | |
Another antifungal, inhibiting ergosterol synthesis, which might indirectly affect Tup1-Ssn6 processes. | ||||||