SSc5D Inhibitors
SSc5D inhibitors are a class of chemical compounds specifically designed to target and inhibit the activity of SSc5D, a protein belonging to the scavenger receptor family. SSc5D (Scavenger Receptor Cysteine-Rich Family Member with 5 Domains) is known for its role in recognizing and binding a broad range of ligands, including lipoproteins, glycoproteins, and other cellular debris. These proteins are involved in immune modulation, playing a part in clearing dead cells, pathogens, and other materials from the extracellular environment. SSc5D is believed to contribute to cellular processes related to immune defense, inflammation regulation, and tissue homeostasis. By inhibiting SSc5D, these compounds interfere with its ability to bind to its ligands, disrupting normal scavenger receptor-mediated processes.
The mechanism of action of SSc5D inhibitors typically involves binding to the ligand-binding domains of the protein, particularly its cysteine-rich domains, which are responsible for ligand recognition and interaction. By blocking these sites, the inhibitors prevent SSc5D from engaging with its natural ligands, thus impairing its role in clearing extracellular debris or modulating immune responses. Some inhibitors may function by inducing conformational changes in SSc5D that reduce its affinity for ligands, while others might directly block the receptor's ability to interact with target molecules. Inhibiting SSc5D affects various cellular processes, particularly those involved in immune response and the maintenance of tissue homeostasis. Research into SSc5D inhibitors provides valuable insights into how scavenger receptors contribute to clearing cellular debris and pathogens, revealing the broader significance of these receptors in regulating immune function and maintaining cellular equilibrium. Understanding SSc5D and its inhibitors also highlights the intricate roles scavenger receptors play in modulating extracellular environments and responding to stress or damage in tissues.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Marimastat | 154039-60-8 | sc-202223 sc-202223A sc-202223B sc-202223C sc-202223E | 5 mg 10 mg 25 mg 50 mg 400 mg | $168.00 $218.00 $404.00 $629.00 $4900.00 | 19 | |
Marimastat inhibits MMPs which are involved in the extracellular matrix remodeling. By inhibiting MMPs, marimastat may prevent the remodeling of the extracellular environment necessary for SC5D to properly interact with its ligands, thus inhibiting the functional activity of SC5D. | ||||||
Batimastat | 130370-60-4 | sc-203833 sc-203833A | 1 mg 10 mg | $179.00 $377.00 | 24 | |
Batimastat, like Marimastat, is an inhibitor of MMPs. Given that SC5D's function can be associated with the integrity and composition of the extracellular matrix, the inhibition of MMPs by Batimastat can lead to reduced remodeling of the extracellular space, thereby inhibiting the interaction of SC5D with extracellular ligands and its subsequent functional activity. | ||||||
GM 6001 | 142880-36-2 | sc-203979 sc-203979A | 1 mg 5 mg | $77.00 $270.00 | 55 | |
GM6001, also known as Ilomastat, inhibits MMPs that are implicated in the turnover of the extracellular matrix, which is crucial for the functioning of SC5D. By inhibiting these proteases, GM6001 can inhibit the function of SC5D by altering the extracellular landscape and the availability of its ligands. | ||||||
SB-3CT | 292605-14-2 | sc-205847 sc-205847A | 1 mg 5 mg | $102.00 $388.00 | 15 | |
SB-3CT is a selective inhibitor of MMP-2 and MMP-9. Since SC5D's action may be intimately linked to the extracellular matrix dynamics and the proteolytic activity of MMPs, inhibition by SB-3CT can lead to a reduction in matrix remodeling, which is necessary for SC5D's activity. | ||||||
Prinomastat | 192329-42-3 | sc-507449 | 5 mg | $190.00 | ||
Prinomastat is an MMP inhibitor that could inhibit the functionality of SC5D by preventing the remodeling of the extracellular matrix, which could be integral to the protein's function in interacting with various ligands or in cellular adhesion processes. | ||||||
TAPI-1 | 171235-71-5 | sc-222337 | 1 mg | $669.00 | 15 | |
TAPI-1 is similar to TAPI-0 as an inhibitor of TACE/ADAM17. Inhibition of this protease might affect the activity of SC5D by blocking the shedding of cell surface proteins that interact with SC5D, potentially inhibiting its activity. | ||||||
TAPI-2 | 187034-31-7 | sc-205851 sc-205851A | 1 mg 5 mg | $286.00 $1019.00 | 15 | |
TAPI-2, an ADAM17 inhibitor, may inhibit SC5D by impeding the shedding of cell surface proteins that SC5D interacts with, thus inhibiting its functional activity. | ||||||
PD166793 | 199850-67-4 | sc-202709 | 5 mg | $150.00 | 6 | |
PD166793 is an inhibitor of MMPs, which are involved in the breakdown of extracellular matrix components. Its inhibition of MMPs could inhibit SC5D by altering the extracellular matrix and the availability of its ligands, thus affecting SC5D's functional interactions. | ||||||
Ro 32-3555 | 190648-49-8 | sc-296277 | 10 mg | $413.00 | 2 | |
Ro 32-3555 is an MMP inhibitor that can inhibit the function of SC5D by modifying the extracellular matrix, which is important for the interaction between SC5D and its ligands. By inhibiting MMPs, Ro 32-3555 alters the matrix that SC5D relies on for its activity. | ||||||