Date published: 2026-5-30

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SR-6 Inhibitors

SR-6 inhibitors, as a conceptual class, encompass a range of small molecules designed to interfere with the activity of a specific protein referred to here as SR-6. This class includes compounds that may bind directly to the SR-6 protein or its substrates, altering the protein's ability to catalyze reactions or to interact with other cellular components. These inhibitors can also act on upstream regulators or downstream effectors of SR-6, thereby modulating its functional output. The variety of molecular structures within this class can lead to differential selectivity and modes of action, each tailored to interact with the unique features of the SR-6 protein or its associated signaling pathways. Compounds classified as SR-6 inhibitors may exhibit a diverse range of biochemical properties, allowing them to permeate cellular membranes, resist metabolic breakdown, and achieve sufficient binding affinity and specificity towards SR-6 or related proteins. By adjusting the functional groups and core structures of these molecules, chemists can refine the pharmacodynamic properties of the inhibitors to enhance their inhibitory action. The development of SR-6 inhibitors draws from interdisciplinary research, encompassing structural biology, medicinal chemistry, and systems biology to elucidate the mechanistic pathways through which these compounds exert their effects, as well as to map out the broader cellular consequences of SR-6 inhibition.

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Items 11 to 20 of 23 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

BGC 20-761

17375-63-2sc-361120
sc-361120A
10 mg
50 mg
$155.00
$620.00
(0)

BGC 20-761, an SR-6 acid halide, exhibits exceptional reactivity due to its strong electrophilic nature, facilitating rapid nucleophilic attacks. The compound's unique steric and electronic properties create a favorable environment for the formation of stable acyl complexes. Its distinctive interaction with solvents enhances solubility and reactivity, while its ability to engage in multiple reaction pathways allows for diverse synthetic strategies, making it a versatile reagent in organic chemistry.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

MEK inhibitor, can alter ERK pathway activity, possibly regulating SR-6.

Ro 04-6790 dihydrochloride

202466-68-0sc-396661
10 mg
$150.00
(0)

Ro 04-6790 dihydrochloride, an SR-6 acid halide, exhibits distinctive reactivity due to its highly polarized carbonyl moiety, which facilitates rapid nucleophilic addition. The compound's unique electronic configuration enhances its interaction with various nucleophiles, leading to diverse acylation products. Additionally, its ability to stabilize reactive intermediates through resonance effects allows for efficient transformation pathways, making it a versatile agent in synthetic chemistry.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

p38 MAPK inhibitor, may impact pathways that modulate SR-6 function.

NPS ALX Compound 4a dihydrochloride

299433-10-6sc-204134
sc-204134A
10 mg
50 mg
$169.00
$712.00
(0)

NPS ALX Compound 4a dihydrochloride, classified as an SR-6 acid halide, showcases remarkable reactivity stemming from its electrophilic carbonyl group, which promotes swift nucleophilic attack. The compound's structural features enable it to engage in selective acylation reactions, yielding a variety of derivatives. Its unique steric and electronic properties also facilitate the formation of stable transition states, enhancing reaction kinetics and expanding its utility in complex synthetic routes.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

JNK inhibitor, could affect signaling processes that SR-6 is part of.

Dimebolin dihydrochloride

97657-92-6sc-294348
sc-294348A
sc-294348B
1 mg
5 mg
50 mg
$37.00
$96.00
$384.00
(0)

Dimebolin dihydrochloride, an SR-6 acid halide, exhibits distinctive reactivity due to its highly polarized carbonyl moiety, which enhances its susceptibility to nucleophilic addition. The compound's unique steric hindrance and electronic distribution allow for selective interactions with various nucleophiles, leading to diverse acylation products. Additionally, its ability to stabilize intermediates contributes to efficient reaction pathways, making it a versatile candidate in synthetic chemistry.

SB-258585 dihydrochloride

sc-301789
10 mg
$185.00
(0)

SB-258585 dihydrochloride, classified as an SR-6 acid halide, showcases remarkable reactivity stemming from its unique electronic configuration and spatial arrangement. The compound's carbonyl group engages in strong dipole-dipole interactions, facilitating rapid acyl transfer reactions. Its distinctive steric profile promotes selective reactivity with specific nucleophiles, resulting in tailored synthetic pathways. Furthermore, the compound's stability under varying conditions enhances its utility in complex reaction schemes.

BAY 11-7082

19542-67-7sc-200615B
sc-200615
sc-200615A
5 mg
10 mg
50 mg
$62.00
$85.00
$356.00
155
(1)

NF-κB pathway inhibitor, potentially influencing SR-6 mediated signaling.

Asenapine maleate

65576-45-6sc-361110
sc-361110A
10 mg
50 mg
$145.00
$615.00
(0)

Asenapine maleate, an SR-6 acid halide, exhibits intriguing reactivity due to its unique stereochemistry and electronic characteristics. The presence of the maleate moiety introduces a conjugated system that enhances electrophilicity, allowing for efficient nucleophilic attack. Its ability to form stable intermediates during reactions is influenced by intramolecular hydrogen bonding, which can modulate reaction kinetics. Additionally, the compound's solubility profile aids in facilitating diverse synthetic transformations.