Molecular structure of BGC 20-761, CAS Number: 17375-63-2
BGC 20-761 (CAS 17375-63-2)
Application:
BGC 20-761 is a selective, high affinity SR-6 antagonist
CAS Number:
17375-63-2
Molecular Weight:
294.39
Molecular Formula:
C19H22N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
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SDS & Certificate of Analysis
BGC 20-761 is a selective, high affinity 5-HT6 antagonist.
BGC 20-761 (CAS 17375-63-2) References
- 2-Substituted tryptamines: agents with selectivity for 5-HT(6) serotonin receptors. | Glennon, RA., et al. 2000. J Med Chem. 43: 1011-8. PMID: 10715164
- BGC20-761, a novel tryptamine analog, enhances memory consolidation and reverses scopolamine-induced memory deficit in social and visuospatial memory tasks through a 5-HT6 receptor-mediated mechanism. | Mitchell, ES., et al. 2006. Neuropharmacology. 50: 412-20. PMID: 16298400
- 5-HT6 receptor agonist EMD386088 impairs behavioral flexibility and working memory. | Amodeo, DA., et al. 2018. Behav Brain Res. 349: 8-15. PMID: 29715539
- Zebrafish behavioural profiling identifies GABA and serotonin receptor ligands related to sedation and paradoxical excitation. | McCarroll, MN., et al. 2019. Nat Commun. 10: 4078. PMID: 31501447
- Serotonin 6 receptor blockade reduces repetitive behavior in the BTBR mouse model of autism spectrum disorder. | Amodeo, DA., et al. 2021. Pharmacol Biochem Behav. 200: 173076. PMID: 33220385
- The brain serotonin system in autism. | Rodnyy, AY., et al. 2024. Rev Neurosci. 35: 1-20. PMID: 37415576
- Enhancing cognition in neurologic disorders: Potential usefulness of 5-HT6 antagonists[J]. | Wilson C, Terry Jr A V. 2009. Drugs of the Future,., 34(12)..
Inhibitor of:
SR-6.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BGC 20-761, 10 mg | sc-361120 | 10 mg | $155.00 | |||
BGC 20-761, 50 mg | sc-361120A | 50 mg | $620.00 |