Date published: 2025-11-24

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Sprr3 Activators

However, it is essential to recognize the context of Sprr3 and its potential activation. Sprr3, or Small Proline-Rich Protein 3, is a member of the small proline-rich protein family, characterized by its high proline content. These proteins are commonly associated with the formation of the cornified cell envelope in epithelial tissues, contributing to the structural integrity of the skin and other stratified epithelia.

In the scenario where Sprr3 activators exist, one could speculate that these compounds might play a role in modulating the expression or function of Sprr3. Given the nature of Sprr3 in promoting epithelial barrier development, its activation could potentially influence cellular processes related to tissue development, repair, or homeostasis. It is conceivable that Sprr3 activators might engage with signaling pathways or molecular mechanisms involved in the regulation of epithelial cell differentiation or maintenance, ultimately impacting the physiological functions of tissues where Sprr3 is expressed. However, without specific details on the chemical structures or mechanisms of action of Sprr3 activators, any discussion would remain speculative, and further research would be necessary to elucidate their potential biological significance.

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

1α,25-Dihydroxyvitamin D3

32222-06-3sc-202877B
sc-202877A
sc-202877C
sc-202877D
sc-202877
50 µg
1 mg
5 mg
10 mg
100 µg
$325.00
$632.00
$1428.00
$2450.00
$400.00
32
(2)

It can regulate keratinocyte proliferation and differentiation, potentially influencing Sprr3 expression.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

This compound is known to regulate gene expression during skin development and may affect Sprr3.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin has been reported to exhibit effects on skin cells, which might include modulation of differentiation-related genes.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

EGCG has anti-inflammatory properties and may influence signaling pathways involved in skin barrier function.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
5 g
100 g
250 g
1 kg
5 kg
$32.00
$66.00
$95.00
$188.00
$760.00
13
(1)

By modulating cyclic AMP levels, caffeine can potentially influence pathways that regulate keratinocyte function.

Tazarotene

118292-40-3sc-220193
10 mg
$103.00
(0)

This synthetic retinoid is used in dermatology and could affect gene expression in skin cells.

Calcipotriol

112965-21-6sc-203537
sc-203537A
10 mg
50 mg
$199.00
$816.00
4
(1)

A vitamin D analog that can influence keratinocyte differentiation, and potentially Sprr3 expression.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

PMA can activate protein kinase C, which is involved in signal transduction in skin cells.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$92.00
$209.00
33
(5)

Methotrexate can affect DNA synthesis and cell proliferation, with potential effects on gene regulation.

Hydroquinone

123-31-9sc-204773
sc-204773A
sc-204773B
250 g
1 kg
5 kg
$36.00
$91.00
$392.00
(1)

Used in dermatology, hydroquinone may have an impact on skin cell gene expression.