SPRR2G Activators
SPRR2G Activators encompass a collection of chemicals that can directly or indirectly enhance the functionality of SPRR2G, a protein that contributes to various biological processes. The activators achieve this feat by manipulating specific signaling pathways and cellular processes that SPRR2G is directly involved in. Some of these activators function by directly increasing intracellular levels of cyclic AMP or calcium ions. For instance, Forskolin and Isoprenaline elevate cyclic AMP levels, which can consequently activate SPRR2G. Similarly, Ionomycin and A23187, by raising intracellular calcium levels, could trigger SPRR2G activation.
On the other hand, activators such as Okadaic Acid and Calyculin A work indirectly by inhibiting protein phosphatases, thereby promoting protein phosphorylation, which could lead to SPRR2G activation. Other chemicals like EGCG, Staurosporine, Bisindolylmaleimide I, LY294002, and PD98059 influence various signaling pathways, and can indirectly influence SPRR2G activity. By acting on these specific signaling pathways or biological processes, these chemicals can enhance the functional activity of SPRR2G. This array of chemical activators demonstrates the multiple layers of regulation and activation that SPRR2G is subjected to, underlining its critical role in cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin directly activates adenylyl cyclase, leading to increased levels of cyclic AMP. SPRR2G activity can be enhanced by this since cyclic AMP acts as a second messenger in various cellular pathways that SPRR2G is a part of. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $94.00 $259.00 | 2 | |
Ionomycin selectively binds to calcium ions, leading to an increase in intracellular calcium levels. SPRR2G activity can be triggered by this as it is involved in calcium-dependent processes. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $285.00 $520.00 $1300.00 | 78 | |
Okadaic Acid inhibits protein phosphatases PP1 and PP2A, leading to enhanced protein phosphorylation. SPRR2G activity can be enhanced by this if the protein's functionality involves phosphorylation. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A sc-24000C | 10 µg 100 µg 1 mg | $160.00 $750.00 $3000.00 | 59 | |
Calyculin A inhibits protein phosphatases PP1 and PP2A, promoting phosphorylation processes that could enhance SPRR2G activity. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates Protein Kinase C (PKC), which could phosphorylate and activate SPRR2G, assuming the protein's activity involves PKC-responsive pathways. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187 transports calcium ions, leading to increased intracellular calcium levels. This can enhance SPRR2G activity if the protein's functionality involves calcium-dependent processes. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG is a polyphenol that can influence various signaling pathways. This could enhance SPRR2G activity if those pathways are directly involved in the protein's functionality. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a potent inhibitor of protein kinases, which may lead to the activation of SPRR2G if it's regulated by these enzymes. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $103.00 $237.00 | 36 | |
Bisindolylmaleimide I is a potent and selective inhibitor of PKC, which could potentially enhance the activity of SPRR2G if it's regulated by PKC-dependent pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a potent inhibitor of PI3K, an enzyme involved in various signaling pathways. This can enhance SPRR2G activity if the protein's functionality involves PI3K-dependent pathways. | ||||||