SPINK9 Inhibitors
SPINK9 Inhibitors refer to a range of chemicals that affect the activity of SPINK9 by influencing skin barrier function, keratinocyte activity, and protease activity in the skin. These inhibitors target various cellular and molecular mechanisms within the skin, thereby affecting the functional role of SPINK9. Retinoids like 13-cis-Retinoic acid, Acitretin, and Retinoic Acid, all trans are known for their role in skin differentiation and renewal. They modulate keratinocyte differentiation and proliferation, which can have downstream effects on the skin barrier function where SPINK9 is involved. By altering the dynamics of skin renewal, these compounds may indirectly influence SPINK9's activity in maintaining skin integrity. Glucocorticoids, including Hydrocortisone and Dexamethasone, and other immunosuppressants like FK-506, Rapamycin, Methotrexate, Azathioprine, and Cyclosporin A, are used to modulate inflammatory responses and immune activity in the skin. These compounds can influence the skin's microenvironment, impacting the expression and function of protease inhibitors like SPINK9.
Urea and Salicylic Acid are used in research for their hydrating and exfoliating properties. By influencing skin hydration and turnover, these agents can affect the conditions under which SPINK9 operates, modulating its activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
13-cis-Retinoic acid | 4759-48-2 | sc-205568 sc-205568A | 100 mg 250 mg | $74.00 $118.00 | 8 | |
A retinoid affecting skin differentiation and turnover, potentially impacting SPINK9. | ||||||
Acitretin | 55079-83-9 | sc-210754 | 25 mg | $148.00 | 1 | |
A synthetic retinoid, influences keratinocyte differentiation, indirectly affecting SPINK9. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A form of vitamin A affecting skin renewal, may indirectly influence SPINK9. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
A Steroid that modulates inflammation and skin processes, potentially affecting SPINK9. | ||||||
Urea | 57-13-6 | sc-29114 sc-29114A sc-29114B | 1 kg 2 kg 5 kg | $30.00 $42.00 $76.00 | 17 | |
Used in dermatology to hydrate and exfoliate skin, indirectly influencing SPINK9 activity. | ||||||
Salicylic acid | 69-72-7 | sc-203374 sc-203374A sc-203374B | 100 g 500 g 1 kg | $46.00 $92.00 $117.00 | 3 | |
A keratolytic agent, may influence skin barrier function and indirectly affect SPINK9. | ||||||
FK-506 | 104987-11-3 | sc-24649 sc-24649A | 5 mg 10 mg | $76.00 $148.00 | 9 | |
An immunosuppressant used in dermatology, may indirectly influence SPINK9 in skin. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, affects cell proliferation and differentiation, potentially impacting SPINK9. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
An immunosuppressant and anti-inflammatory, may indirectly affect SPINK9 in skin processes. | ||||||
Azathioprine | 446-86-6 | sc-210853D sc-210853 sc-210853A sc-210853B sc-210853C | 500 mg 1 g 2 g 5 g 10 g | $199.00 $173.00 $342.00 $495.00 $690.00 | 1 | |
An immunosuppressive drug, could indirectly impact skin homeostasis and SPINK9. | ||||||