Acitretin is a synthetic retinoid, the major metabolite of etretinate (sc-205689). It has demonstrated an ability to suppress the development of chemically-induced epithelial tumors, as well as squamous cell carcinoma.
1. Liu, Xin., et al., 2008. Comparison of the in vitro and in vivo effects of retinoids either alone or in combination with cisplatin and 5-fluorouracil on tumor development and metastasis of melanoma. Cancer chemotherapy and pharmacology. 63(1): 167-74. PMID: 18465132 2. Sato, Tomohiro., et al., 2008. In silico functional profiling of small molecules and its applications. Journal of medicinal chemistry. 51(24): 7705-16. PMID: 19032081
Soluble in Warm Chloroform
Store at -80° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Thank you for your question. The compound, sc-210754, is provided as a yellow or greenish-yellow crystalline powder. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected], or using the Live Chat function on our website.
Rated 5 out of
HolthoewerHolthoewer, D. et al. (PubMed 22301853) reported that Acitretin, an enhancer of -secretase expression, crosses the blood-brain barrier and is not eliminated by P-glycoprotein. -SCBT Publication Review
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