The SPINK13 Inhibitors chemical class is characterized by a collection of compounds that indirectly modulate the activity of the SPINK13 protein. This class includes a broad range of kinase inhibitors, such as Staurosporine, LY294002, U0126, SB203580, Wortmannin, PD98059, ZM447439, LY3214996, and Selumetinib, each targeting specific signaling pathways. The presence of Rapamycin, a well-known mTOR inhibitor, indicates the class's potential influence on cell growth and survival pathways, which are crucial for understanding the biological functions of SPINK13.
Histone deacetylase inhibitors like Trichostatin A also form a significant part of this class, suggesting an interest in gene expression regulation related to SPINK13. The inclusion of Aurora kinase and JNK inhibitors, represented by ZM447439 and SP600125, further diversifies the class, pointing to the possible roles of cell division and stress response pathways in modulating SPINK13 activity.
This class exemplifies a strategic approach to indirectly influence SPINK13, focusing on the broader network of signaling pathways and gene expression mechanisms. The diversity of mechanisms within this class highlights the complex nature of SPINK13's role in cellular biology and the need for a multifaceted approach to modulate its activity
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent protein kinase inhibitor, affects multiple signaling pathways that may intersect with SPINK13's regulatory mechanisms. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, may alter cell growth and survival pathways, potentially influencing SPINK13's biological functions. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor, can modulate signaling pathways indirectly linked to SPINK13's function in cellular processes. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
A MEK inhibitor, potentially affects MAPK/ERK signaling which could have implications for SPINK13 activity. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor, could influence stress response pathways intersecting with SPINK13's role. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A PI3K inhibitor, may impact signaling pathways that indirectly modulate SPINK13's function. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A MEK inhibitor, could modify MAPK/ERK pathway, potentially influencing pathways associated with SPINK13. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $150.00 $349.00 | 15 | |
An Aurora kinase inhibitor, could affect cell division pathways indirectly related to SPINK13's role. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor, can alter gene expression patterns potentially affecting SPINK13 regulation. | ||||||
LY3214996 | 1951483-29-6 | sc-507299 | 5 mg | $260.00 | ||
An ERK1/2 inhibitor, potentially affects signaling pathways that may intersect with SPINK13's activity. | ||||||