SPCS2 Activators
SPCS2 play diverse roles in facilitating its function within the cellular environment. Oleic acid, a monounsaturated fatty acid, integrates into cellular membranes, which can enhance membrane fluidity, thus aiding the insertion and function of SPCS2 in the lipid bilayer. This action is crucial because SPCS2 activity is related to its membrane-bound status, where it participates in protein processing. Similarly, cholesterol serves to stabilize membrane structures, which can optimize the microenvironment for SPCS2, promoting its correct folding and function within the lipid bilayer. Phosphatidylserine, another lipid component of the cell membrane, supports the localization and function of SPCS2 in membrane assembly and protein sorting, ensuring that SPCS2 is correctly positioned to interact with substrates and other cellular machinery.
lysophosphatidic acid and sphingosine-1-phosphate are lipid signaling molecules that can activate pathways leading to cytoskeletal reorganization and cell survival, respectively. These pathways are crucial as they can facilitate a context that is conducive to SPCS2 activity, particularly in the realm of protein trafficking. Phosphatidylinositol 4,5-bisphosphate (PIP2), though a minor membrane component, is a potent activator of signal transduction pathways that can provide a suitable membrane environment for SPCS2 activation. Arachidonic acid, released during membrane turnover, engages in signaling that can lead to the activation of proteins, which includes the potential to activate SPCS2. Likewise, docosahexaenoic acid (DHA) and ceramide can enhance membrane fluidity and initiate signaling cascades, respectively, creating an environment that can aid in the activation of SPCS2. Diacylglycerol (DAG) serves as a second messenger in the activation of protein kinase C, which can then phosphorylate proteins in its vicinity, possibly leading to the activation of SPCS2. Furthermore, farnesol, involved in the prenylation of proteins, can facilitate proper membrane association and activation of SPCS2. Finally, retinoic acid, by influencing cell differentiation and proliferation, can establish a cellular state that is permissive to SPCS2 activation, ensuring that the protein is in an optimal state for its function within the cell.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Oleic Acid | 112-80-1 | sc-200797C sc-200797 sc-200797A sc-200797B | 1 g 10 g 100 g 250 g | $36.00 $102.00 $569.00 $1173.00 | 10 | |
Oleic acid integrates into cellular membranes, enhancing membrane fluidity, which can facilitate the insertion and function of SPCS2 in the lipid bilayer. | ||||||
L-α-Lecithin, Egg Yolk, Highly Purified | 8002-43-5 | sc-203096 | 250 mg | $78.00 | ||
Phosphatidylserine is a component of the inner leaflet of the plasma membrane and may support the appropriate localization and function of SPCS2 in membrane assembly and protein sorting. | ||||||
Cholesterol | 57-88-5 | sc-202539C sc-202539E sc-202539A sc-202539B sc-202539D sc-202539 | 5 g 5 kg 100 g 250 g 1 kg 25 g | $26.00 $2754.00 $126.00 $206.00 $572.00 $86.00 | 11 | |
Cholesterol is known to stabilize membrane structures and may optimize the microenvironment for SPCS2 activation by promoting its correct folding and function within the lipid bilayer. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $71.00 $260.00 $485.00 $949.00 | ||
Lysophosphatidic acid can activate signaling pathways that lead to cytoskeletal reorganization, potentially facilitating SPCS2 activity related to protein processing and trafficking. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
Sphingosine-1-phosphate is involved in signaling pathways that govern cell survival and proliferation, which might enhance the cellular context for SPCS2 activation and its associated functions. | ||||||
Arachidonic Acid (20:4, n-6) | 506-32-1 | sc-200770 sc-200770A sc-200770B | 100 mg 1 g 25 g | $90.00 $235.00 $4243.00 | 9 | |
Arachidonic acid is released during membrane phospholipid turnover and can be involved in signaling pathways that lead to the activation of proteins, possibly including SPCS2. | ||||||
Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3) | 6217-54-5 | sc-200768 sc-200768A sc-200768B sc-200768C sc-200768D | 100 mg 1 g 10 g 50 g 100 g | $92.00 $206.00 $1744.00 $7864.00 $16330.00 | 11 | |
DHA is an omega-3 fatty acid that can enhance membrane fluidity, potentially facilitating the membrane integration and functional activation of SPCS2. | ||||||
C2 Ceramide | 3102-57-6 | sc-201375 sc-201375A | 5 mg 25 mg | $77.00 $316.00 | 12 | |
Ceramide can initiate a variety of signaling cascades that may influence the membrane dynamics and protein interactions necessary for SPCS2 activation. | ||||||
R 59-022 | 93076-89-2 | sc-203227 | 5 mg | $122.00 | 1 | |
DAG is a second messenger that activates protein kinase C, potentially phosphorylating and activating proteins in proximity, which could include SPCS2. | ||||||
Farnesol | 4602-84-0 | sc-204748 sc-204748A | 50 ml 100 ml | $275.00 $367.00 | 2 | |
Farnesol is involved in the prenylation process, which could facilitate the proper membrane association and function of membrane proteins, including SPCS2. | ||||||