Date published: 2026-3-9

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SPARC Antibodies

Santa Cruz Biotechnology features a diverse variety of SPARC Antibodies for advanced research in cellular and molecular biology. SPARC Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). SPARC, also known as Secreted Protein Acidic and Rich in Cysteine, plays a vital role in cell-matrix interactions, influencing processes such as tissue remodeling, wound healing, and tumor progression. SPARC expression is frequently linked to various pathological conditions, making it an important target for understanding disease mechanisms and developing therapeutic strategies. Researchers can investigate SPARC's role in extracellular matrix organization and cellular adhesion using specific detection methods. Advanced imaging techniques enable visualization of SPARC localization within cellular compartments. Multiple conjugation options are available, including horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC), allowing for versatile experimental approaches. Santa Cruz Biotechnology monoclonal antibodies for SPARC research support scientists worldwide in advancing our understanding of cellular processes and disease mechanisms.

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SPARC Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SPARC Antibody (D-2)

sc-398419mouse IgG2b κ1-90 (h)WB, IP, IF, IHC(P), ELISAh
6
(12)

SPARC Antibody (AON-1)

sc-33645mouse IgG3 κFL (bovine)WB, IP, IFm, r, h
8
(7)

SPARC Antibody (AON-5031)

sc-73472mouse IgG1(h)WB, IP, IF, IHC(P)m, r, h
17
(7)

SPARCL1 Antibody (G-5)

sc-514275mouse IgM κ586-600 (m)WB, IP, IF, ELISAm, r, h
5
(1)

SPARCL1 Antibody (D-1)

sc-390199mouse IgG1 κN-terminal (h)WB, IP, IF, ELISAh
2
(2)

SPARCL1 Antibody (F-8)

sc-514262mouse IgG2a κ586-600 (m)WB, IP, IF, ELISAm, r, h

new

(1)

SPARC CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPARC CRISPR/Cas9 KO Plasmid (h)

sc-400566hGene KnockoutGFP0
(0)

SPARC HDR Plasmid (h)

sc-400566-HDRhHomology Directed RepairPuromycin0
(0)

SPARC CRISPR/Cas9 KO Plasmid (m)

sc-423101mGene KnockoutGFP0
(0)

SPARC Double Nickase Plasmid (m)

sc-423101-NICmGene KnockoutPuromycin0
(0)

SPARC Double Nickase Plasmid (m2)

sc-423101-NIC-2mGene KnockoutPuromycin0
(0)

SPARC CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPARC CRISPR Activation Plasmid (h)

sc-400566-ACThGene ActivationPuro, Blast, Hygro0
(0)

SPARC CRISPR Activation Plasmid (h2)

sc-400566-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SPARC CRISPR Activation Plasmid (m)

sc-423101-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SPARC CRISPR Activation Plasmid (m2)

sc-423101-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SPARC Lentiviral Activation Particles (m)

sc-423101-LACmGene ActivationPuro, Blast, Hygro0
(0)

SPARCL1 CRISPR Activation Plasmid (h)

sc-404048-ACThGene ActivationPuro, Blast, Hygro0
(0)

SPARC siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPARC siRNA (h)

sc-37166hGene SilencingN/A
3
(0)

SPARC shRNA Plasmid (h)

sc-37166-SHhGene SilencingPuromycin
3
(0)

SPARC shRNA (h) Lentiviral Particles

sc-37166-VhGene SilencingPuromycin
3
(0)

SPARC siRNA (m)

sc-41034mGene SilencingN/A0
(0)

SPARC shRNA Plasmid (m)

sc-41034-SHmGene SilencingPuromycin0
(0)

SPARC shRNA (m) Lentiviral Particles

sc-41034-VmGene SilencingPuromycin0
(0)

SPARCL1 siRNA (h)

sc-89018hGene SilencingN/A0
(0)

SPARCL1 shRNA Plasmid (h)

sc-89018-SHhGene SilencingPuromycin0
(0)

SPARCL1 shRNA (h) Lentiviral Particles

sc-89018-VhGene SilencingPuromycin0
(0)