SNX27 Activators
SNX27 activators belong to a distinct chemical class of compounds that play a pivotal role in cellular processes, particularly within the realm of intracellular trafficking and signal transduction pathways. These activators are characterized by their ability to modulate the activity of sorting nexin 27 (SNX27), a multifunctional protein that is instrumental in the regulation of endocytic trafficking and membrane protein recycling. SNX27 itself is a member of the sorting nexin family, which comprises a group of cytoplasmic proteins recognized for their involvement in membrane dynamics, vesicular trafficking, and endosomal sorting. SNX27 activators are chemical compounds that have been identified and developed to specifically enhance the activity or stability of SNX27 within cells.
At a molecular level, SNX27 activators are designed to interact with SNX27 or its associated protein partners to either stimulate its function or stabilize its structure. The precise mechanisms through which these activators operate can vary, but their ultimate impact is on the trafficking of membrane proteins, such as receptors and transporters, within the endosomal system. SNX27 activators can promote the recycling of specific membrane proteins back to the cell surface, preventing their degradation or promoting their reutilization.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels. This elevation can indirectly influence SNX27 by modulating signaling pathways affecting protein trafficking. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which can indirectly influence SNX27 by altering cellular signaling pathways involved in membrane trafficking. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic Acid, a Vitamin A derivative, can indirectly influence SNX27 by modulating gene expression patterns related to cellular trafficking and sorting mechanisms. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187, a calcium ionophore, can indirectly affect SNX27 by altering intracellular calcium levels, important for various signaling pathways including those related to protein trafficking. | ||||||
Sodium nitroprusside dihydrate | 13755-38-9 | sc-203395 sc-203395A sc-203395B | 1 g 5 g 100 g | $42.00 $83.00 $155.00 | 7 | |
Sodium nitroferricyanide, a nitric oxide donor, can indirectly affect SNX27 by modulating signaling pathways involved in membrane dynamics and trafficking. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride affects several signaling pathways and can indirectly influence SNX27 by altering the balance of secondary messengers and modulating pathways involved in protein sorting. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin has various biological effects and can influence SNX27 indirectly through its effects on cellular signaling and membrane dynamics. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a polyphenol, can affect immune functions and may impact SNX27 activity indirectly through its immunomodulatory effects and influence on cellular signaling. | ||||||
Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3) | 6217-54-5 | sc-200768 sc-200768A sc-200768B sc-200768C sc-200768D | 100 mg 1 g 10 g 50 g 100 g | $92.00 $206.00 $1744.00 $7864.00 $16330.00 | 11 | |
DHA, an Omega-3 fatty acid, influences lipid metabolism and signaling pathways, potentially affecting SNX27 activity indirectly by modulating membrane composition and related protein sorting mechanisms. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
N-Acetyl-L-cysteine, an antioxidant, can influence cellular redox states. It may indirectly affect SNX27 by modulating oxidative stress-related signaling pathways that influence protein trafficking. | ||||||