Date published: 2026-4-1

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Smok3b Inhibitors

Smok3b inhibitors are a class of chemical compounds designed to specifically target and inhibit the activity of the Smok3b protein, a member of the Smokin gene family, which is involved in various cellular processes, particularly those related to signal transduction and gene regulation. Smok3b is known to play a role in regulating intracellular signaling pathways that influence cellular growth, differentiation, and responses to external stimuli. By modulating these pathways, Smok3b contributes to the regulation of gene expression, protein synthesis, and the overall maintenance of cellular homeostasis. Inhibitors of Smok3b work by blocking its ability to interact with other proteins or signaling molecules, thereby disrupting its role in the regulation of these critical pathways.

Researchers use Smok3b inhibitors to study the specific mechanisms by which Smok3b influences cellular signaling and how its inhibition affects broader biological processes. These inhibitors are valuable tools for exploring the interactions between Smok3b and other proteins in the cell, revealing how this protein modulates signal transduction pathways and contributes to complex networks of cellular communication. By inhibiting Smok3b, scientists can investigate the downstream effects on gene expression, protein interactions, and cellular dynamics, which may provide deeper insights into the regulation of cell behavior and homeostasis. The study of Smok3b inhibitors is essential for advancing the understanding of intracellular signaling mechanisms and the roles of regulatory proteins like Smok3b in maintaining cellular function.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$153.00
$396.00
113
(4)

A broad-spectrum kinase inhibitor that could potentially affect various kinases involved in sperm motility.

Bisindolylmaleimide I (GF 109203X)

133052-90-1sc-24003A
sc-24003
1 mg
5 mg
$105.00
$242.00
36
(1)

Targets PKC, which may influence pathways involved in sperm motility.

H-89 dihydrochloride

130964-39-5sc-3537
sc-3537A
1 mg
10 mg
$94.00
$186.00
71
(2)

A PKA inhibitor, potentially impacting cAMP-dependent signaling mechanisms crucial for sperm motility.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

Inhibits MEK1/2, potentially affecting the MAPK/ERK pathway involved in sperm motility regulation.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

A PI3K inhibitor, which might influence signaling pathways crucial for the regulation of sperm motility.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

JNK inhibitor, potentially affecting stress response pathways that could influence sperm motility.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

Inhibits p38 MAP kinase, possibly affecting inflammatory response pathways involved in sperm motility regulation.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

Another potent inhibitor of PI3K, affecting cellular processes including those relevant to sperm motility.

KN-93

139298-40-1sc-202199
1 mg
$182.00
25
(1)

Specifically inhibits CaMKII, involved in calcium signaling pathways that are crucial for motility.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$186.00
$707.00
88
(1)

A ROCK inhibitor, potentially affecting cytoskeleton dynamics critical for sperm motility.