Date published: 2026-5-16

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Smok2b Inhibitors

Smok2b inhibitors are a class of chemical compounds designed to specifically target and block the activity of the Smok2b protein. Smok2b is part of the Smokin gene family, a group of proteins that are involved in various intracellular processes, including gene regulation, signal transduction, and potentially cellular differentiation. Though the precise functions of Smok2b are not fully understood, it is believed to play a role in modulating pathways that control cellular responses to external stimuli and internal signaling. By influencing these pathways, Smok2b can impact cell growth, survival, and communication within complex biological networks. Inhibitors of Smok2b are crafted to interfere with its normal function, either by blocking its active sites or preventing it from interacting with other regulatory proteins or signaling molecules.

Using Smok2b inhibitors allows researchers to study the detailed mechanisms by which this protein influences cellular processes. By inhibiting Smok2b, scientists can observe the downstream effects on gene expression, protein synthesis, and the regulation of cellular signaling pathways. This provides a better understanding of how Smok2b fits into larger cellular networks, particularly those involved in growth and differentiation. Additionally, Smok2b inhibitors are valuable tools for dissecting the interactions between the Smokin protein family and other key cellular components, revealing how these proteins help coordinate essential biological functions. By focusing on Smok2b's regulatory roles, researchers can uncover new insights into the molecular dynamics of signal transduction and gene regulation, further expanding the understanding of how cells control complex processes.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$153.00
$396.00
113
(4)

A potent, broad-spectrum kinase inhibitor that may affect kinases involved in sperm motility.

Bisindolylmaleimide I (GF 109203X)

133052-90-1sc-24003A
sc-24003
1 mg
5 mg
$105.00
$242.00
36
(1)

Inhibits protein kinase C (PKC), which could play a role in the regulation of sperm motility.

H-89 dihydrochloride

130964-39-5sc-3537
sc-3537A
1 mg
10 mg
$94.00
$186.00
71
(2)

Targets protein kinase A (PKA), potentially impacting cAMP-dependent pathways crucial for sperm motility.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

MEK1/2 inhibitor, potentially affecting the MAPK/ERK pathway relevant to sperm motility regulation.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

Inhibits phosphoinositide 3-kinases (PI3K), which may influence signaling pathways involved in sperm motility.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

JNK inhibitor, potentially affecting sperm motility through stress response pathways.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

Inhibits p38 MAP kinase, possibly influencing pathways involved in sperm motility regulation.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

Another potent PI3K inhibitor, affecting cellular processes including sperm motility.

KN-93

139298-40-1sc-202199
1 mg
$182.00
25
(1)

Specifically inhibits Ca2+/calmodulin-dependent protein kinase II (CaMKII), involved in calcium signaling relevant to motility.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$186.00
$707.00
88
(1)

Inhibits Rho-associated, coiled-coil containing protein kinase (ROCK), affecting cytoskeleton dynamics crucial for motility.