Slfn13 Activators
Slfn13 Activators are a collection of chemical compounds that can directly or indirectly enhance the functional activity of Slfn13 through their influence on specific cellular or biochemical pathways. Resveratrol and Forskolin, for instance, act on Slfn13 indirectly through the activation of the SIRT1 and adenylate cyclase pathways respectively. Resveratrol's activation of the SIRT1 pathway leads to deacetylation of proteins that can enhance Slfn13 functional activity by promoting optimal cellular homeostasis. Similarly, Forskolin's activation of the adenylate cyclase pathway increases intracellular cAMP levels, thereby enhancing Slfn13 functional activity by optimizing its transport conditions.
Furthermore, other Slfn13 Activators like EGCG, Curcumin, Silymarin, Quercetin, and Genistein act by inhibiting pathways that produce proteins known to negatively regulate Slfn13. EGCG and Silymarin inhibit the NF-κB pathway, reducing the production of proteins that negatively regulate Slfn13, hence enhancing its functional activity. Similarly, Curcumin, Quercetin, and Genistein inhibit the JAK-STAT and PI3K/AKT pathways, consequently reducing the production of proteins that can negatively regulate Slfn13, thereby further enhancing its functional activity. Also, Capsaicin and Piperine function by activating the TRPV1 pathway,which leads to changes in the ionic balance within the cell, optimizing transport conditions that enhance Slfn13 activity.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol enhances Slfn13 indirectly by activating the SIRT1 pathway. SIRT1, a NAD+-dependent deacetylase, deacetylates numerous proteins, promoting optimal cellular homeostasis for Slfn13 operation. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin enhances Slfn13 indirectly by activating the adenylate cyclase pathway. This activation increases intracellular levels of cAMP, optimizing the transport conditions for Slfn13. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG enhances Slfn13 indirectly by inhibiting the NF-κB pathway. This inhibition reduces the production of proteins that negatively regulate Slfn13, enhancing its functional activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin enhances Slfn13 indirectly by inhibiting the JAK-STAT pathway. By inhibiting this pathway, Curcumin reduces the production of proteins that negatively regulate Slfn13, enhancing its functional activity. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
Capsaicin enhances Slfn13 indirectly by activating the TRPV1 pathway, which leads to changes in ionic balance in the cell. These changes optimize the transport conditions for Slfn13, enhancing its functional activity. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $42.00 $62.00 $153.00 $255.00 $500.00 $30.00 | 37 | |
Metformin enhances Slfn13 indirectly by activating the AMPK pathway. AMPK optimizes metabolism and energy homeostasis. The activation of AMPK optimizes the cellular energy status for Slfn13 operation, enhancing its functional activity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin enhances Slfn13 indirectly by inhibiting the PI3K/AKT pathway. By inhibiting this pathway, Quercetin reduces the production of proteins that negatively regulate Slfn13, enhancing its functional activity. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $90.00 | 1 | |
Berberine enhances Slfn13 indirectly by activating the AMPK pathway, similar to Metformin. By activating AMPK, Berberine optimizes the cellular energy status for Slfn13 operation, enhancing its functional activity. | ||||||
Silymarin group, mixture of isomers | 65666-07-1 | sc-301806 | 50 g | $319.00 | ||
Silymarin enhances Slfn13 indirectly by inhibiting the NF-κB pathway, similar to EGCG. By inhibiting NF-κB, Silymarin reduces the production of proteins that negatively regulate Slfn13, enhancing its functional activity. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein enhances Slfn13 indirectly by inhibiting the PI3K/AKT pathway, similar to Quercetin. By inhibiting this pathway, Genistein reduces the production of proteins that negatively regulate Slfn13, enhancing its functional activity. | ||||||