Slfn12L Activators
Slfn12L Activators are a collection of chemical compounds that can directly or indirectly enhance the functional activity of Slfn12L through their influence on specific cellular or biochemical pathways. For instance, Resveratrol and Forskolin act on Slfn12L indirectly through the activation of the SIRT1 and adenylate cyclase pathways respectively. Resveratrol's activation of the SIRT1 pathway leads to deacetylation of proteins that can enhance Slfn12L functional activity by promoting optimal cellular homeostasis. Similarly, Forskolin's activation of the adenylate cyclase pathway increases intracellular cAMP levels, thereby enhancing Slfn12L functional activity by optimizing its transport conditions.
Additionally, other Slfn12L Activators like EGCG, Curcumin, Silymarin, Quercetin, and Genistein act by inhibiting pathways that produce proteins known to negatively regulate Slfn12L. EGCG and Silymarin inhibit the NF-κB pathway, reducingthe production of proteins that negatively regulate Slfn12L, hence enhancing its functional activity. Similarly, Curcumin, Quercetin, and Genistein inhibit the JAK-STAT and PI3K/AKT pathways, consequently reducing the production of proteins that can negatively regulate Slfn12L, thereby further enhancing its functional activity.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol enhances Slfn12L indirectly by activating the SIRT1 pathway. SIRT1, a NAD+-dependent deacetylase, deacetylates numerous proteins. This deacetylation can enhance the function of Slfn12L by promoting optimal cellular homeostasis for its operation. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin enhances Slfn12L indirectly by activating the adenylate cyclase pathway. This activation increases intracellular levels of cAMP, a second messenger. Increased cAMP levels can enhance Slfn12L functional activity by optimizing its transport conditions. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG enhances Slfn12L indirectly by inhibiting the NF-κB pathway. This inhibition reduces the production of proteins that negatively regulate Slfn12L, thereby enhancing its functional activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin enhances Slfn12L indirectly by inhibiting the JAK-STAT pathway. By inhibiting this pathway, Curcumin can reduce the production of proteins that negatively regulate Slfn12L, thereby enhancing its functional activity. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin enhances Slfn12L indirectly by activating the TRPV1 pathway, which can lead to changes in ionic balance in the cell. These changes can indirectly enhance Slfn12L functional activity by optimizing its transport conditions. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
Metformin enhances Slfn12L indirectly by activating the AMPK pathway. AMPK is a cellular energy sensor that optimizes metabolism and energy homeostasis. The activation of AMPK can enhance the functional activity of Slfn12L by optimizing the cellular energy status for its operation. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin enhances Slfn12L indirectly by inhibiting the PI3K/AKT pathway. By inhibiting this pathway, Quercetin can reduce the production of proteins that negatively regulate Slfn12L, thereby enhancing its functional activity. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine enhances Slfn12L indirectly by activating the AMPK pathway, similar to Metformin. By activating AMPK, Berberine can enhance the functional activity of Slfn12L by optimizing the cellular energy status for its operation. | ||||||
Silymarin group, mixture of isomers | 65666-07-1 | sc-301806 | 50 g | $325.00 | ||
Silymarin enhances Slfn12L indirectly by inhibiting the NF-κB pathway, similar to EGCG. By inhibiting NF-κB, Silymarin can enhance the functional activity of Slfn12L by reducing the production of proteins that negatively regulate it. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein enhances Slfn12L indirectly by inhibiting the PI3K/AKT pathway, similar to Quercetin. By inhibiting this pathway, Genistein can reduce the production of proteins that negatively regulate Slfn12L, thereby enhancing its functional activity. | ||||||