SLC35A5 Activators
SLC35A5 Activators are a diverse group of chemical compounds that can indirectly enhance the functional activity of SLC35A5, a solute carrier protein, by influencing various signaling pathways. For instance, Resveratrol and Forskolin act by activating the SIRT1 and adenylate cyclase pathways respectively. The SIRT1 pathway, when activated by Resveratrol, leads to the deacetylation of numerous proteins that can indirectly affect the actions of SLC35A5. Similarly, Forskolin's activation of the adenylate cyclase pathway increases the intracellular levels of cAMP, a second messenger, which can indirectly lead to the enhanced functional activity of SLC35A5.
Additionally, Capsaicin and Piperine activate the TRPV1 pathway, which is involved in pain and heat sensation. These compounds, by activating this pathway, can indirectly enhance the functional activity of SLC35A5. Other compounds such as EGCG, Curcumin, Silymarin, Quercetin, and Genistein act by inhibiting various pathways, including the NF-κB and PI3K/AKT pathwayswhich are involved in regulating the expression of various genes and cell growth and survival, respectively. By inhibiting these pathways, these compounds indirectly enhance the functional activity of SLC35A5. Furthermore, Metformin and Berberine activate the AMPK pathway, a cellular energy sensor that regulates metabolism and energy homeostasis. Through the activation of this pathway, these compounds can indirectly enhance the functional activity of SLC35A5. Lastly, Sulforaphane, a sulfur-rich compound, activates the Nrf2 antioxidant pathway, which can indirectly lead to the enhanced functional activity of SLC35A5.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is a polyphenol that is known to activate the SIRT1 pathway. SIRT1, a NAD+-dependent deacetylase, is capable of deacetylating a wide variety of proteins. SLC35A5, a solute carrier protein, can be indirectly affected by the actions of SIRT1, thereby enhancing its functional activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is a labdane diterpene that activates the adenylate cyclase pathway. Adenylate cyclase activation increases the intracellular levels of cAMP, a second messenger, which can indirectly lead to the enhanced functional activity of SLC35A5. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a catechin that is known to inhibit the NF-κB pathway. NF-κB is a family of transcription factors that regulate the expression of a variety of genes. The inhibition of NF-κB could indirectly enhance the functional activity of SLC35A5. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is a polyphenolic compound that can inhibit the JAK-STAT signaling pathway. This pathway regulates a variety of cellular processes, including cell proliferation and immune response. By inhibiting the JAK-STAT pathway, Curcumin can indirectly enhance the functional activity of SLC35A5. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin activates the TRPV1 pathway, which is involved in pain and heat sensation. Activation of this pathway can indirectly lead to the enhanced functional activity of SLC35A5. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
Metformin activates the AMPK pathway. AMPK is a cellular energy sensor that regulates metabolism and energy homeostasis. The activation of AMPK could indirectly enhance the functional activity of SLC35A5. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid that inhibits the PI3K/AKT pathway. The PI3K/AKT pathway is involved in cell survival and growth. By inhibiting this pathway, Quercetin can indirectly enhance the functional activity of SLC35A5. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine activates the AMPK pathway, similar to Metformin. Activation of AMPK could indirectly enhance the functional activity of SLC35A5. | ||||||
Silymarin group, mixture of isomers | 65666-07-1 | sc-301806 | 50 g | $325.00 | ||
Silymarin is a flavonoid that inhibits the NF-κB pathway, making it similar to EGCG. The inhibition of NF-κB could indirectly enhance the functional activity of SLC35A5. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein is an isoflavone that inhibits the PI3K/AKT pathway. Similar to Quercetin, by inhibiting this pathway, Genistein can indirectly enhance the functional activity of SLC35A5. | ||||||