SLAM Activators
The chemical class of SLAM Activators comprises a range of compounds that could potentially influence the activity of SLAM (Signaling Lymphocytic Activation Molecule), also known as SLAMF1, indirectly. SLAM/SLAMF1 is a critical receptor on immune cells, playing a significant role in modulating immune responses, including the activation and differentiation of T cells and B cells. The modulation of SLAM/SLAMF1 is intricately linked to various cellular signaling pathways and immune regulatory mechanisms.
Compounds such as Forskolin, which increases cAMP levels, and Phorbol 12-myristate 13-acetate (PMA), an activator of protein kinase C, demonstrate their potential to influence SLAM/SLAMF1 activity through modulation of key signaling pathways within immune cells. Forskolin's role in elevating cAMP levels and PMA's activation of PKC highlight the complex interplay between cellular signaling and the regulation of immune co-stimulatory receptors like SLAM/SLAMF1. Additionally, immunomodulatory agents like Cyclosporine A and Rapamycin, known for their effects on T-cell activation and mTOR signaling, respectively, could indirectly affect SLAM/SLAMF1 activity.
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Increases cAMP levels, potentially modulating immune cell signaling pathways affecting SLAM/SLAMF1. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C (PKC), which could influence SLAM/SLAMF1 activity through PKC-mediated pathways. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Modulates various signaling pathways, potentially affecting SLAM/SLAMF1 activity in immune cells. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Influences various signaling pathways, potentially modulating SLAM/SLAMF1 activity. | ||||||
Prostratin | 60857-08-1 | sc-203422 sc-203422A | 1 mg 5 mg | $141.00 $541.00 | 24 | |
Activates PKC, could influence SLAM/SLAMF1 through cellular signaling pathways. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
An immunosuppressant that affects T-cell activation, potentially influencing SLAM/SLAMF1 indirectly. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor, could affect SLAM/SLAMF1 activity through modulation of T-cell activation and differentiation. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
A glucocorticoid, might modulate SLAM/SLAMF1 activity through anti-inflammatory pathways. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Regulates immune responses, could indirectly affect SLAM/SLAMF1 expression and function. | ||||||
Aspirin | 50-78-2 | sc-202471 sc-202471A | 5 g 50 g | $20.00 $42.00 | 4 | |
An NSAID, could potentially influence SLAM/SLAMF1 activity through its anti-inflammatory effects. | ||||||