SH3BGRL Inhibitors
Items 1 to 10 of 17 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a potent inhibitor of protein kinases, including PKC. SH3BGR, as part of the SH3 domain-containing proteins, can interact with proline-rich motifs of proteins involved in signaling pathways, such as those activated by PKC. Inhibition of PKC by Staurosporine can, therefore, prevent the activation of proteins bound by SH3BGR, leading to its functional inhibition. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a potent inhibitor of PI3K, which is involved in multiple signaling pathways. Considering that SH3BGR can bind to proteins that are downstream targets of PI3K, inhibition of this kinase can indirectly lead to decreased functional activity of SH3BGR. | ||||||
SU6656 | 330161-87-0 | sc-203286 sc-203286A | 1 mg 5 mg | $57.00 $133.00 | 27 | |
Src family kinase inhibitor, similar to PP2, potentially altering SH3 domain-mediated signaling. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
A tyrosine kinase inhibitor that can inhibit Src kinases and may affect SH3 domain interactions. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a selective inhibitor of MEK, which is upstream of ERK in the MAPK pathway. Since SH3BGR can bind to proteins in the MAPK pathway, inhibiting MEK and thus reducing ERK activation can lead to decreased functional activity of SH3BGR. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 is a selective inhibitor of ROCK, which is involved in actin cytoskeleton reorganization. Given that SH3BGR binds to proteins involved in actin remodeling, inhibition of ROCK can indirectly lead to decreased functional activity of SH3BGR. | ||||||
Herbimycin A | 70563-58-5 | sc-3516 sc-3516A | 100 µg 1 mg | $277.00 $1532.00 | 13 | |
Tyrosine kinase inhibitor that may disrupt interactions with SH3 domain-containing proteins. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
PP2 is an inhibitor of Src family kinases, which are known to interact with SH3 domain-containing proteins. PP2 can inhibit the functional activity of SH3BGR by preventing the activation of proteins that interact with SH3BGR. | ||||||
PIK-75, hydrochloride | 372196-77-5 | sc-296089 sc-296089A | 1 mg 5 mg | $29.00 $124.00 | ||
PI3K inhibitor that could influence downstream signaling pathways associated with SH3 domain interactions. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of JNK, a kinase involved in various signaling pathways. Since SH3BGR can bind to proteins that are downstream targets of JNK, inhibiting this kinase can indirectly lead to decreased functional activity of SH3BGR. | ||||||