Date published: 2025-12-19

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Serotonergics

Santa Cruz Biotechnology now offers a broad range of Serotonergics for use in various applications. Serotonergics are a category of chemical compounds that modulate the serotonin system, which is a critical neurotransmitter system in both central and peripheral nervous systems. These compounds play a vital role in scientific research by enabling the study of serotonin's functions and its impact on various biological processes. Serotonergics include agonists, antagonists, and reuptake inhibitors that allow researchers to manipulate serotonin levels and receptor activity to investigate their effects on mood regulation, cognitive functions, and other physiological responses. In neurobiology and behavioral science, these compounds are essential for understanding the mechanisms underlying neurotransmission, synaptic plasticity, and the neural basis of behavior. By using serotonergics, scientists can explore the complex interactions between serotonin and other neurotransmitter systems, providing insights into the neural circuits involved in various behaviors and physiological processes. The availability of high-purity serotonergics supports robust and reproducible experimental outcomes, facilitating the development of new experimental models and the discovery of novel regulatory mechanisms within the serotonin system. Through these studies, researchers can uncover fundamental principles of neural function and develop new hypotheses about the role of serotonin in health and disease. Santa Cruz Biotechnology's comprehensive selection of serotonergics equips researchers with the precise tools needed to advance their understanding of this essential neurotransmitter system. View detailed information on our available Serotonergics by clicking on the product name.

Items 71 to 80 of 215 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Paroxetine maleate

64006-44-6sc-203658
sc-203658A
10 mg
50 mg
$172.00
$712.00
(0)

Paroxetine maleate functions as a serotonergic compound by engaging in selective interactions with serotonin transporters, showcasing a unique affinity for specific binding sites. Its molecular design facilitates distinct electrostatic interactions and steric hindrance, which influence its kinetic behavior in solution. The maleate salt form enhances its stability and solubility, allowing for effective modulation of serotonin levels through altered transport dynamics and receptor engagement.

MK 212 hydrochloride

64022-27-1sc-203634
sc-203634A
10 mg
50 mg
$115.00
$473.00
(0)

MK 212 hydrochloride acts as a serotonergic agent by modulating serotonin receptor activity, particularly influencing 5-HT2 receptor subtypes. Its structural conformation allows for unique hydrogen bonding and hydrophobic interactions, which enhance receptor affinity. The hydrochloride form contributes to its solubility and stability in aqueous environments, facilitating rapid distribution and interaction kinetics. This compound's behavior is characterized by its ability to alter neurotransmitter release dynamics through specific receptor engagement.

Urapidil HCl

64887-14-5sc-200155
100 mg
$122.00
(0)

Urapidil HCl functions as a serotonergic compound by selectively engaging with serotonin receptors, notably impacting the 5-HT1A and 5-HT2 subtypes. Its unique molecular architecture promotes specific electrostatic interactions and conformational flexibility, enhancing binding efficacy. The hydrochloride salt form increases its solubility, allowing for efficient diffusion across biological membranes. This compound exhibits distinct modulation of neurotransmitter pathways, influencing synaptic transmission and receptor signaling cascades.

Fluperlapine

67121-76-0sc-201119
sc-201119A
sc-201119B
1 mg
5 mg
10 mg
$51.00
$232.00
$408.00
2
(1)

Fluperlapine acts as a serotonergic agent by intricately modulating serotonin receptor activity, particularly influencing the 5-HT2A subtype. Its unique structural features facilitate specific hydrogen bonding and hydrophobic interactions, optimizing receptor affinity. The compound's dynamic conformation allows for enhanced receptor engagement, leading to nuanced alterations in intracellular signaling pathways. Additionally, its physicochemical properties contribute to its stability and reactivity in various environments, influencing its overall behavior in biochemical systems.

5-Carboxamidotryptamine maleate

74885-09-9sc-203477
sc-203477A
5 mg
25 mg
$302.00
$1086.00
2
(0)

5-Carboxamidotryptamine maleate functions as a serotonergic compound by selectively engaging with serotonin receptors, notably the 5-HT1A subtype. Its unique amide group enhances binding affinity through specific electrostatic interactions, promoting receptor activation. The compound exhibits distinct kinetic profiles, influencing the rate of receptor-ligand interactions. Furthermore, its solubility characteristics and stability in aqueous environments facilitate its behavior in biological systems, impacting downstream signaling cascades.

Amperozide hydrochloride

86725-37-3sc-203512
sc-203512A
10 mg
50 mg
$520.00
$1543.00
2
(1)

Amperozide hydrochloride acts as a serotonergic agent by modulating serotonin receptor activity, particularly influencing the 5-HT2A receptor subtype. Its unique structural features, including a specific arrangement of functional groups, enable it to form hydrogen bonds and hydrophobic interactions, enhancing receptor affinity. The compound's dynamic conformational changes contribute to its interaction kinetics, allowing for varied receptor activation profiles. Additionally, its solubility in polar solvents aids in its distribution and interaction within complex biological matrices.

WAY 161503 hydrochloride

276695-22-8sc-204392
sc-204392A
5 mg
25 mg
$94.00
$376.00
(1)

WAY 161503 hydrochloride functions as a serotonergic compound by selectively engaging with serotonin receptors, notably the 5-HT1A subtype. Its distinctive molecular architecture facilitates specific electrostatic interactions and steric effects, which enhance binding affinity. The compound exhibits unique reaction kinetics, characterized by rapid association and dissociation rates, allowing for nuanced modulation of receptor signaling. Furthermore, its amphiphilic nature promotes effective integration into lipid membranes, influencing its bioavailability and interaction dynamics.

2-Methylserotonin Hydrochloride

78263-90-8 (free base)sc-201136
sc-201136A
10 mg
50 mg
$113.00
$525.00
1
(0)

2-Methylserotonin Hydrochloride acts as a serotonergic agent by selectively targeting serotonin receptors, particularly the 5-HT3 subtype. Its unique structural features enable specific hydrogen bonding and hydrophobic interactions, enhancing receptor affinity. The compound demonstrates distinctive reaction kinetics, with a propensity for rapid conformational changes that influence receptor activation. Additionally, its solubility profile allows for effective diffusion across biological membranes, impacting its interaction with cellular environments.

Sertraline hydrochloride

79559-97-0sc-201104
sc-201104A
sc-201104B
10 mg
50 mg
100 mg
$67.00
$102.00
$153.00
2
(1)

Sertraline hydrochloride functions as a serotonergic compound by modulating serotonin transport mechanisms, particularly influencing the serotonin reuptake process. Its unique molecular structure facilitates specific electrostatic interactions with transporter proteins, enhancing binding affinity. The compound exhibits notable stability in aqueous environments, promoting effective solvation dynamics. Furthermore, its ability to form transient complexes with target proteins underscores its role in altering neurotransmitter availability and signaling pathways.

rac-trans-Sertraline

79836-45-6sc-212762
25 mg
$360.00
(0)

Rac-trans-Sertraline exhibits distinct characteristics as a serotonergic agent, primarily through its selective inhibition of serotonin reuptake transporters. The compound's stereochemistry allows for unique conformational flexibility, enabling it to engage in specific hydrogen bonding and hydrophobic interactions with receptor sites. This interaction profile contributes to its kinetic behavior, influencing the rate of serotonin modulation. Additionally, its solubility properties enhance its distribution in biological systems, facilitating dynamic interactions with various biomolecules.