Molecular structure of Amperozide hydrochloride, CAS Number: 86725-37-3
Amperozide hydrochloride (CAS 86725-37-3)
See product citations (2)
Alternate Names:
4-[4,4-bis(4-Fluorophenyl)butyl]-N-ethyl-1-piperazinecarboxamide hydrochloride
Application:
Amperozide hydrochloride is a compound displaying high affinity for 5-HT2 receptors
CAS Number:
86725-37-3
Purity:
≥98%
Molecular Weight:
437.95
Molecular Formula:
C23H29F2N3O•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Amperozide hydrochloride is a research chemical that has gained interest due to its unique interaction with neurotransmitter systems. In neuroscientific research, it is primarily used to study the modulation of dopamine receptors and the subsequent effects on neurochemical pathways. Its ability to cross the blood-brain barrier allows for in-depth investigation into the central nervous system′s response to dopaminergic modulation. Furthermore, in the area of neuropharmacology, amperozide hydrochloride serves as a tool to decipher the molecular underpinnings of receptor dynamics and signaling pathways, particularly in the context of dopaminergic function and regulation.
Amperozide hydrochloride (CAS 86725-37-3) References
- Tiospirone and the reinforcing effects of cocaine in the conditioned place preference paradigm in rats. | Arolfo, MP. and McMillen, BA. 2000. J Pharm Pharmacol. 52: 977-81. PMID: 11007069
- Effect of amperozide on rat cortical 5-HT2 and striatal and limbic dopamine D2 receptor occupancy: implications for antipsychotic action. | Meltzer, HY., et al. 1992. Eur J Pharmacol. 216: 67-71. PMID: 1388121
- Validating a firefly luciferase-based high-throughput screening assay for antimalarial drug discovery. | Che, P., et al. 2012. Assay Drug Dev Technol. 10: 61-8. PMID: 22050430
- Amphetamine and cocaine suppress social play behavior in rats through distinct mechanisms. | Achterberg, EJ., et al. 2014. Psychopharmacology (Berl). 231: 1503-15. PMID: 24057815
- Novel cell-based hepatitis C virus infection assay for quantitative high-throughput screening of anti-hepatitis C virus compounds. | Hu, Z., et al. 2014. Antimicrob Agents Chemother. 58: 995-1004. PMID: 24277038
- Biochemical and electrophysiological studies of the psychotropic compound, amperozide. | Haskins, JT., et al. 1987. Brain Res Bull. 19: 465-71. PMID: 2825928
- Antiarrhythmic effect of amperozide, a novel psychotropic compound with class III antiarrhythmic properties, on digoxin-induced arrhythmias in the guinea-pig. | Höglund, P., et al. 1986. J Pharm Pharmacol. 38: 861-3. PMID: 2879024
- Effects of amperozide on biting behavior and performance in restricted-fed pigs following regrouping. | Björk, A., et al. 1988. J Anim Sci. 66: 669-75. PMID: 3378924
- Systemic administration of amperozide, a new atypical antipsychotic drug, preferentially increases dopamine release in the rat medial prefrontal cortex. | Nomikos, GG., et al. 1994. Psychopharmacology (Berl). 115: 147-56. PMID: 7862887
- 5-HT2 receptor blockade by amperozide suppresses ethanol drinking in genetically preferring rats. | Myers, RD., et al. 1993. Pharmacol Biochem Behav. 45: 741-7. PMID: 8332634
- Synthesis of dopamine and 5-HT in anatomical regions of the rat's brain is unaffected by sustained infusion of amperozide. | Adell, A. and Myers, RD. 1995. Pharmacol Toxicol. 77: 341-5. PMID: 8778747
- Risperidone: regional effects in vivo on release and metabolism of dopamine and serotonin in the rat brain. | Hertel, P., et al. 1996. Psychopharmacology (Berl). 124: 74-86. PMID: 8935802
- Identification of amperozide metabolites in urine from rats, rabbits, dogs and man by Frit-FAB LC/MS using deuterated solvents to gain additional structural information | P. O. Edlund. 1995. Journal of Mass Spectrometry. 30: 1380-1392.
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CCK-AR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Amperozide hydrochloride, 10 mg | sc-203512 | 10 mg | $520.00 | |||
Amperozide hydrochloride, 50 mg | sc-203512A | 50 mg | $1574.00 |