SCHIP1 activators consist of an array of chemical compounds that potentially modulate the activity or functionality of SCHIP1 indirectly through various interconnected signaling pathways and cellular processes. For instance, Forskolin operates by elevating intracellular cAMP levels, which can have a ripple effect through a plethora of cellular cascades, potentially crossing paths with those associated with SCHIP1. Similarly, compounds like U0126, PD98059, and SB203580, which target different steps in the MAPK pathway, shed light on the extensive connectivity of intracellular signaling networks and how they can indirectly influence the functionality of proteins like SCHIP1.
Furthermore, inhibitors of the PI3K pathway, like Wortmannin and LY294002, exemplify the intricate balance of phosphatidylinositol signaling in cells, highlighting the potential cross-talk between different pathways and SCHIP1. Additionally, the impact on Ras signaling by agents such as Manumycin A and FTS elucidates the significance of small GTPases and their downstream effectors in orchestrating a vast range of cellular activities.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Inhibits proteasome, potentially affecting protein turnover and function associated with SCHIP1. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
By inhibiting PI3K, it may affect pathways intersecting with SCHIP1 functionality. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Another PI3K inhibitor; its effect can influence pathways potentially associated with SCHIP1. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Modulates the Golgi apparatus and can potentially affect cellular processes linked with SCHIP1. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
By inhibiting protein phosphatases, it can modulate phosphorylation status of proteins that might relate to SCHIP1. | ||||||
Manumycin A | 52665-74-4 | sc-200857 sc-200857A | 1 mg 5 mg | $219.00 $634.00 | 5 | |
Affects Ras signaling, and thereby, can influence associated cellular pathways that intersect with SCHIP1. | ||||||
Farnesyl thiosalicylic acid | 162520-00-5 | sc-205322 sc-205322A | 1 mg 5 mg | $61.00 $82.00 | 15 | |
By targeting Ras, it may indirectly affect processes or pathways linked with SCHIP1. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
Inhibits MEK1, another step in the MAPK pathway, potentially influencing SCHIP1-related processes. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
By inhibiting p38 MAPK, it can potentially modulate cellular pathways that intersect with SCHIP1. | ||||||