Date published: 2025-10-30

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RRP15 Activators

RRP15 activators are compounds belonging to a chemical class engineered to interact with and modulate the activity of the RRP15 protein. RRP15, also known as Ribosomal RNA Processing 15, is a protein involved in ribosome biogenesis, a fundamental cellular process necessary for protein synthesis. Ribosome biogenesis encompasses the complex assembly of ribosomal subunits, essential components of the cellular machinery responsible for translating messenger RNA (mRNA) into proteins. RRP15 plays a critical role in this process by participating in the maturation of ribosomal RNA (rRNA), a key step in ribosome assembly. Specifically, RRP15 is involved in the processing of precursor rRNA transcripts, facilitating the cleavage and modification events required for the generation of mature rRNA molecules. Through its involvement in ribosome biogenesis, RRP15 contributes to the regulation of protein synthesis and cellular growth.

Research into RRP15 activators focuses on elucidating the molecular mechanisms underlying their interaction with the RRP15 protein and understanding how this interaction influences ribosome biogenesis and cellular processes. Understanding the pharmacological properties of these compounds is essential for deciphering how they modulate RRP15 activity and potentially impact ribosome assembly and protein synthesis. By unraveling the biological functions and regulatory mechanisms of RRP15, researchers aim to deepen our understanding of cellular biology and may uncover novel insights into the molecular pathways governing ribosome biogenesis and protein synthesis. Continued exploration of RRP15 activators holds promise for advancing our knowledge of cellular physiology and may provide insights into new strategies for manipulating ribosome function and protein synthesis in experimental contexts.

SEE ALSO...

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic acid can regulate gene expression by activating nuclear receptors, which may influence ribosomal biogenesis.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Forskolin activates adenylate cyclase, raising cAMP levels and potentially affecting transcription factors related to ribosome biogenesis.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

EGCG can modulate signal transduction pathways, possibly altering the transcription of genes involved in ribosomal assembly.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Actinomycin D intercalates into DNA, influencing RNA synthesis; low doses might selectively affect rRNA transcription.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$88.00
$200.00
13
(1)

Triptolide might influence transcriptional activity by affecting RNA polymerase II, which could alter ribosome biogenesis.

Oxamflatin

151720-43-3sc-205960
sc-205960A
1 mg
5 mg
$148.00
$461.00
4
(1)

Oxamflatin is an HDAC inhibitor, which may lead to histone hyperacetylation and affect gene expression related to ribosome biogenesis.

Rocaglamide

84573-16-0sc-203241
sc-203241A
sc-203241B
sc-203241C
sc-203241D
100 µg
1 mg
5 mg
10 mg
25 mg
$270.00
$465.00
$1607.00
$2448.00
$5239.00
4
(1)

Rocaglamide can inhibit translation initiation and has the potential to indirectly affect transcription of ribosomal components.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$42.00
$185.00
$310.00
$650.00
6
(1)

DRB inhibits RNA polymerase II, potentially leading to a compensatory response in ribosome biogenesis-related gene expression.

Homoharringtonine

26833-87-4sc-202652
sc-202652A
sc-202652B
1 mg
5 mg
10 mg
$51.00
$123.00
$178.00
11
(1)

Homoharringtonine is known to inhibit protein translation, which could secondarily alter ribosome biogenesis gene expression.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$97.00
$254.00
36
(2)

Anisomycin interferes with protein synthesis, potentially triggering a stress response affecting ribosome biogenesis genes.