RRP15 activators are compounds belonging to a chemical class engineered to interact with and modulate the activity of the RRP15 protein. RRP15, also known as Ribosomal RNA Processing 15, is a protein involved in ribosome biogenesis, a fundamental cellular process necessary for protein synthesis. Ribosome biogenesis encompasses the complex assembly of ribosomal subunits, essential components of the cellular machinery responsible for translating messenger RNA (mRNA) into proteins. RRP15 plays a critical role in this process by participating in the maturation of ribosomal RNA (rRNA), a key step in ribosome assembly. Specifically, RRP15 is involved in the processing of precursor rRNA transcripts, facilitating the cleavage and modification events required for the generation of mature rRNA molecules. Through its involvement in ribosome biogenesis, RRP15 contributes to the regulation of protein synthesis and cellular growth.
Research into RRP15 activators focuses on elucidating the molecular mechanisms underlying their interaction with the RRP15 protein and understanding how this interaction influences ribosome biogenesis and cellular processes. Understanding the pharmacological properties of these compounds is essential for deciphering how they modulate RRP15 activity and potentially impact ribosome assembly and protein synthesis. By unraveling the biological functions and regulatory mechanisms of RRP15, researchers aim to deepen our understanding of cellular biology and may uncover novel insights into the molecular pathways governing ribosome biogenesis and protein synthesis. Continued exploration of RRP15 activators holds promise for advancing our knowledge of cellular physiology and may provide insights into new strategies for manipulating ribosome function and protein synthesis in experimental contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid can regulate gene expression by activating nuclear receptors, which may influence ribosomal biogenesis. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, raising cAMP levels and potentially affecting transcription factors related to ribosome biogenesis. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG can modulate signal transduction pathways, possibly altering the transcription of genes involved in ribosomal assembly. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA, influencing RNA synthesis; low doses might selectively affect rRNA transcription. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide might influence transcriptional activity by affecting RNA polymerase II, which could alter ribosome biogenesis. | ||||||
Oxamflatin | 151720-43-3 | sc-205960 sc-205960A | 1 mg 5 mg | $148.00 $461.00 | 4 | |
Oxamflatin is an HDAC inhibitor, which may lead to histone hyperacetylation and affect gene expression related to ribosome biogenesis. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $270.00 $465.00 $1607.00 $2448.00 $5239.00 | 4 | |
Rocaglamide can inhibit translation initiation and has the potential to indirectly affect transcription of ribosomal components. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB inhibits RNA polymerase II, potentially leading to a compensatory response in ribosome biogenesis-related gene expression. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $51.00 $123.00 $178.00 | 11 | |
Homoharringtonine is known to inhibit protein translation, which could secondarily alter ribosome biogenesis gene expression. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Anisomycin interferes with protein synthesis, potentially triggering a stress response affecting ribosome biogenesis genes. | ||||||