RPAP2 Activators represent a specialized class of chemical compounds or molecules that have attracted attention within the field of molecular biology and cellular research. These activators are designed or discovered with the specific aim of modulating the activity of the RPAP2 gene. RPAP2, or RNA Polymerase II Associated Protein 2, is a protein-coding gene found in humans and other organisms. It encodes a protein that plays a role in RNA polymerase II (RNAPII) transcription, a critical process in gene expression, and regulation.
The study of RPAP2 activators is intriguing because it allows researchers to explore the precise role of the RPAP2 gene in cellular physiology and molecular mechanisms related to transcriptional regulation. Activation of RPAP2 can offer valuable insights into its potential involvement in facilitating the function of RNAPII, which is responsible for transcribing protein-coding genes into messenger RNA (mRNA). By manipulating the activity of RPAP2 through these activators, scientists aim to gain a deeper understanding of the complex molecular pathways and cellular functions that rely on the gene product, thereby contributing to the broader knowledge of gene regulation and cellular behavior. Consequently, RPAP2 activators serve as valuable tools for researchers dedicated to unraveling the intricate molecular mechanisms that govern cellular biology and the specific roles played by individual genes in these processes, particularly within the context of transcriptional control and mRNA synthesis.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
May demethylate DNA, potentially leading to the activation of silenced genes, including RPAP2. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An HDAC inhibitor, which could lead to changes in chromatin structure and potentially upregulate RPAP2 expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Could modify glycogen synthase kinase-3 (GSK-3) activity, potentially influencing RPAP2 gene expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Raises cAMP levels, which could trigger a signaling cascade affecting transcription factors regulating RPAP2 expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
As an HDAC inhibitor, it could enhance the acetylation of histones near the RPAP2 gene, possibly upregulating its expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Through its receptor-mediated action, retinoic acid might alter the transcription of genes, possibly including RPAP2. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
A cAMP analog that could mimic the effects of cAMP, potentially influencing RPAP2 expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
This catechin could affect DNA methylation and histone modification, potentially altering RPAP2 gene expression. | ||||||
Mifepristone | 84371-65-3 | sc-203134 | 100 mg | $60.00 | 17 | |
By modulating glucocorticoid receptor signaling, it could influence the transcriptional regulation of RPAP2. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
Phosphodiesterase inhibitor which could increase intracellular cAMP, potentially affecting RPAP2 expression. |