RNF113B Activators
RNF113B Activators can be understood as chemicals that indirectly influence the activity of RNF113B, a protein involved in the DNA damage response and the ubiquitin-proteasome system. These compounds generally function either by causing DNA damage, thereby inducing the DNA damage response involving RNF113B, or by inhibiting the proteasome, thereby potentially affecting the ubiquitin-proteasome system involving RNF113B. For instance, hydroxyurea, doxorubicin, cisplatin, etoposide, camptothecin, and bleomycin can induce DNA damage, thereby potentially inducing the DNA damage response involving RNF113B. Moreover, MG132, bortezomib, carfilzomib, MLN2238, epoxomicin, and marizomib function by inhibiting the proteasome, thereby potentially affecting the ubiquitin-proteasome system involving RNF113B.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Hydroxyurea induces replication stress, leading to DNA damage, triggering DNA damage response involving RNF113B. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
Doxorubicin intercalates into DNA, causing DNA damage and potentially inducing the DNA damage response involving RNF113B. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
Cisplatin causes DNA damage, leading to replication stress and potentially inducing the DNA damage response involving RNF113B. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Etoposide inhibits topoisomerase II, leading to DNA damage and potentially inducing the DNA damage response involving RNF113B. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Camptothecin inhibits topoisomerase I, leading to DNA damage and potentially inducing the DNA damage response involving RNF113B. | ||||||
Bleomycin | 11056-06-7 | sc-507293 | 5 mg | $270.00 | 5 | |
Bleomycin induces DNA strand breaks, causing DNA damage and potentially inducing the DNA damage response involving RNF113B. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG132 inhibits the proteasome, potentially affecting the ubiquitin-proteasome system involving RNF113B. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Bortezomib inhibits the proteasome, potentially affecting the ubiquitin-proteasome system involving RNF113B. | ||||||
Carfilzomib | 868540-17-4 | sc-396755 | 5 mg | $40.00 | ||
Carfilzomib inhibits the proteasome, potentially affecting the ubiquitin-proteasome system involving RNF113B. | ||||||
Ixazomib | 1072833-77-2 | sc-489103 sc-489103A | 10 mg 50 mg | $311.00 $719.00 | ||
MLN2238 inhibits the proteasome, potentially affecting the ubiquitin-proteasome system involving RNF113B. | ||||||