Ribosomal Protein S27 Activators
Ribosomal Protein S27 (RPS27) is a fundamental component of the ribosome, specifically associated with the 40S subunit of eukaryotic ribosomes. Ribosomes, being the cellular machinery responsible for protein synthesis, consist of RNA and protein molecules, with RPS27 being one of the essential proteins.RPS27 plays a crucial role in the assembly and structural stability of the ribosome. It is involved in binding ribosomal RNA and is important for the proper function of the ribosome during translation, the process where the genetic code from mRNA is decoded into amino acid sequences to form proteins.
In addition to its role in protein synthesis, RPS27 is also implicated in cellular responses to stress and in the regulation of cell growth and proliferation. Like other ribosomal proteins, the expression of RPS27 is tightly controlled and can be influenced by various intracellular and extracellular signals, reflecting the cell's metabolic state and demands for protein synthesis.Given its integral role in ribosomal function, RPS27 has been studied in the context of various diseases, including cancer. Alterations in ribosomal biogenesis and function, often involving ribosomal proteins such as RPS27, can contribute to tumorigenesis and the progression of malignancies.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
May influence RPS27 expression as it regulates cell growth and differentiation, which demand increased protein synthesis. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR pathway regulates ribosome biogenesis; inhibitors may initially decrease but eventually stabilize RPS27 expression. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Interferes with DNA-dependent RNA synthesis; low doses could selectively affect transcription of ribosomal RNA and proteins. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $69.00 $266.00 | 8 | |
By inhibiting inosine monophosphate dehydrogenase, it could alter nucleotide pools and affect RPS27 expression. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
A nucleotide analog that may disrupt RNA processing and potentially alter ribosomal protein expression including RPS27. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As an HDAC inhibitor, could promote a more open chromatin state, potentially increasing transcription of ribosomal proteins. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Through sirtuin activation, it could affect cellular stress response pathways, potentially upregulating RPS27 expression. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
Oxidative stress can induce a cellular response leading to increased protein synthesis requirements and RPS27 expression. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Regulates cellular growth and differentiation, which may require increased ribosomal protein synthesis, including RPS27. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc is essential for cell growth; deficiencies may alter protein synthesis and the expression of ribosomal proteins. | ||||||