Rhox4e Activators
The chemical class known as Rhox4e Activators encompasses a diverse range of compounds that can influence the expression and activity of the reproductive homeobox 4E (Rhox4e) gene. These activators operate through various mechanisms to impact the transcriptional regulation of Rhox4e, thereby affecting its role in reproductive tissue development and function. Members of this class can interact with cellular signaling pathways by binding to specific receptors, which in turn can lead to changes in gene expression. For instance, some can bind to nuclear hormone receptors, triggering a cascade of transcriptional regulation that can upregulate the expression of target genes, including those that influence reproductive development.
Other activators in this class can modulate the epigenetic landscape of the cell, affecting the expression of Rhox4e. By inhibiting enzymes responsible for DNA methylation or histone deacetylation, these activators can alter chromatin structure, resulting in a more transcriptionally active state that can lead to increased expression of Rhox4e. Additionally, some members of this class can influence cellular second messenger systems, such as the cAMP pathway, which can activate protein kinases involved in the phosphorylation of transcription factors. These phosphorylated transcription factors can modulate the expression of Rhox4e, either directly or through intermediary factors. Collectively, these mechanisms demonstrate the complex interplay between these activators and the cellular machinery that governs gene expression.
The Rhox4e Activators class is characterized by its ability to interact with intracellular processes that control gene regulation. These compounds can act on the transcriptional machinery or the epigenetic environment to facilitate an increase in Rhox4e expression. Through the modulation of signaling pathways, alteration of epigenetic markers, and manipulation of second messenger systems, Rhox4e Activators can enhance the cellular conditions favorable for the expression of Rhox4e. The diversity of this chemical class is reflected in the variety of molecular targets and pathways they influence, encompassing a range of biochemical interactions that converge on the upregulation of Rhox4e expression. These activators work in concert with the cell's regulatory systems to maintain and promote the function of Rhox4e within the realm of reproductive biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Influences gene expression through retinoid receptors, which could possibly activate Rhox4e by leading to the activation of genes involved in reproductive tissue development. | ||||||
Diethylstilbestrol | 56-53-1 | sc-204720 sc-204720A sc-204720B sc-204720C sc-204720D | 1 g 5 g 25 g 50 g 100 g | $70.00 $281.00 $536.00 $1076.00 $2142.00 | 3 | |
A synthetic estrogen that binds to estrogen receptors and modulates gene expression, which could possibly activate Rhox4e by leading to upregulation of genes in reproductive tissues. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylyl cyclase, increasing cAMP levels, which in turn activates PKA; PKA could possibly activate Rhox4e by phosphorylating transcription factors that may upregulate its expression. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
A DNA methyltransferase inhibitor that could possibly activate Rhox4e by demethylating DNA and leading to the transcriptional activation of some genes. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An HDAC inhibitor that could possibly activate Rhox4e by leading to a more open chromatin structure and facilitating gene transcription. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Also an HDAC inhibitor, which could possibly activate Rhox4e by potentially increasing histone acetylation and promoting transcriptional activation of genes. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Known to alter DNA methylation and histone modifications, which could possibly activate Rhox4e by increasing the expression of genes. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
A cAMP analog that activates PKA, which could possibly activate Rhox4e by leading to activation of transcription factors that enhance its expression. | ||||||
Zebularine | 3690-10-6 | sc-203315 sc-203315A sc-203315B | 10 mg 25 mg 100 mg | $126.00 $278.00 $984.00 | 3 | |
A DNA methyltransferase inhibitor that could possibly activate Rhox4e by leading to DNA demethylation and subsequent activation of certain genes. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
A tyrosine kinase inhibitor that could possibly activate Rhox4e by modulating cell signaling pathways and altering gene regulation. | ||||||