Rhox2f inhibitors are a class of chemical compounds designed to specifically target and inhibit the function of Rhox2f, a transcription factor that belongs to the Rhox (Reproductive Homeobox) gene family. Rhox2f plays an important role in regulating gene expression, particularly in the development and function of reproductive tissues. Like other homeobox proteins, Rhox2f contains a conserved DNA-binding domain that allows it to bind to specific regulatory sequences within the genome, controlling the transcription of genes that are crucial for cellular differentiation, growth, and development. These inhibitors function by interacting with key regions of Rhox2f, such as its DNA-binding domain, thereby preventing it from binding to target DNA sequences and disrupting its regulatory activity. This interference leads to the inhibition of Rhox2f's ability to control gene expression networks involved in cellular function.
The inhibition of Rhox2f disrupts the transcriptional programs that depend on its regulatory influence, particularly in developmental processes and reproductive tissue maintenance. By blocking Rhox2f, these inhibitors impact the normal expression of genes that are essential for proper cell growth and differentiation, leading to altered cellular functions and developmental pathways. Researchers use Rhox2f inhibitors as molecular tools to explore the specific roles of this transcription factor in gene regulation and to better understand how it contributes to the broader biological processes controlled by the Rhox family. These inhibitors also provide insights into how Rhox2f interacts with other proteins and transcriptional regulators, shedding light on the complex regulatory networks that orchestrate development and cellular specialization. Moreover, Rhox2f inhibitors allow scientists to investigate the evolutionary conservation and functional diversification of Rhox family members across species, offering a deeper understanding of how homeobox genes like Rhox2f have adapted to regulate key biological processes in reproduction and development.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A cytidine analog that inhibits DNA methylation, potentially affecting the expression of homeobox genes including Rhox2f. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An inhibitor of histone deacetylases, which can lead to changes in chromatin structure and influence the expression of genes like Rhox2f. | ||||||
Vinclozolin | 50471-44-8 | sc-251425 | 250 mg | $23.00 | 1 | |
Acts as an anti-androgen, potentially impacting reproductive tissue development and indirectly influencing Rhox2f activity. | ||||||
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
Known to disrupt endocrine functions, which could alter the gene expression patterns in reproductive tissues, potentially impacting Rhox2f. | ||||||
Diethylstilbestrol | 56-53-1 | sc-204720 sc-204720A sc-204720B sc-204720C sc-204720D | 1 g 5 g 25 g 50 g 100 g | $70.00 $281.00 $536.00 $1076.00 $2142.00 | 3 | |
A synthetic estrogen, affecting gene expression in reproductive tissues, which may have implications for Rhox2f expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Influences gene expression during embryonic development and could affect homeobox gene functions including Rhox2f. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
This catechin has epigenetic effects that could influence the expression of genes like Rhox2f. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
A glucocorticoid that modulates gene expression and may indirectly affect Rhox2f. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
A phytoestrogen that can alter gene expression in reproductive tissues, possibly influencing Rhox2f. | ||||||
Zearalenone | 17924-92-4 | sc-204943 sc-204943A | 10 mg 50 mg | $118.00 $362.00 | 6 | |
Exhibits estrogenic activity, which might affect reproductive development and consequently Rhox2f expression. | ||||||