RFWD3 Activators
The class of chemicals known as RFWD3 activators comprises compounds that have to indirectly enhance the expression or activity of the RFWD3 gene or protein by influencing specific cellular processes and signaling pathways known to be associated with RFWD3 regulation. One subset of RFWD3 activators includes DNA-damaging agents such as cisplatin and camptothecin. These compounds are known to induce DNA damage responses in cells, activating pathways that involve RFWD3 in DNA repair. By causing DNA damage, these activators can trigger the cellular mechanisms that lead to increased RFWD3 expression, ultimately contributing to the repair of DNA lesions.
Another group of compounds within the RFWD3 activators class includes those that influence redox signaling and cellular stress responses. N-Acetylcysteine (NAC) and hydrogen peroxide (H2O2), for example, can modulate oxidative stress-related pathways. As RFWD3 is implicated in cellular responses to stress, these chemicals can enhance RFWD3 activity by affecting the cellular redox state and stress signaling, leading to changes in RFWD3 expression levels. Furthermore, histone deacetylase, such as vorinostat, can alter chromatin structure and gene expression patterns. In the context of RFWD3 regulation, these compounds may indirectly influence RFWD3 expression by modifying chromatin accessibility and gene transcription, resulting in enhanced RFWD3 activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Arsenic(III) oxide | 1327-53-3 | sc-210837 sc-210837A | 250 g 1 kg | $87.00 $224.00 | ||
Arsenic trioxide has been shown to activate the p53 pathway, which plays a role in DNA repair and cell cycle regulation. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR activates AMP-activated protein kinase (AMPK) signaling, linked to cellular energy regulation and stress responses. | ||||||
Adenosine 5′-Triphosphate, disodium salt | 987-65-5 | sc-202040 sc-202040A | 1 g 5 g | $38.00 $74.00 | 9 | |
ATP is involved in cellular energy metabolism and signaling pathways, potentially affecting various cellular processes. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
NAC is an antioxidant and a precursor of glutathione, influencing redox signaling pathways and gene expression. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Camptothecin is a topoisomerase I inhibitor, leading to DNA damage and activation of DNA damage response pathways. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Histone deacetylase inhibitors can alter chromatin structure and gene expression, potentially influencing RFWD3 expression. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Caffeine can activate ATR/ATM signaling pathways in response to DNA damage, potentially influencing RFWD3. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
Hydrogen peroxide is a reactive oxygen species (ROS) that can activate stress response pathways, potentially affecting RFWD3. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
Mitomycin C is a DNA cross-linking agent that induces DNA damage responses, potentially affecting RFWD3 expression. | ||||||
Phleomycin | 11006-33-0 | sc-204845 sc-204845A | 5 mg 25 mg | $191.00 $485.00 | ||
Phleomycin is a DNA-damaging antibiotic that can activate DNA damage response pathways, potentially affecting RFWD3. | ||||||