Phleomycin (CAS 11006-33-0)
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Phleomycin is a glycopeptide that is frequently used in molecular biology research for its ability to cleave DNA. As a tool for genetic engineering, it is often employed to select for transfection efficiency, as cells that have not incorporated the desired genetic material do not survive its presence. The mechanism by which phleomycin operates involves binding to DNA and causing strand breaks, a property that is harnessed in the laboratory to study DNA repair processes and the cellular responses to DNA damage. In the field of biochemistry, phleomycin is used to understand the role of metal ions in enzymatic reactions that involve nucleic acids, since the compound requires metal ions to exert its DNA-cleaving activity. Environmental researchers also use phleomycin to investigate the impact of DNA-damaging agents on microorganisms in various ecosystems, contributing to a broader understanding of microbial resistance mechanisms to such compounds.
Phleomycin (CAS 11006-33-0) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Phleomycin, 5 mg | sc-204845 | 5 mg | $195.00 | |||
Phleomycin, 25 mg | sc-204845A | 25 mg | $495.00 |