Reg IV Inhibitors
Reg IV Inhibitors belong to a specialized chemical class with a primary focus on the modulation of a specific protein known as Regenerating islet-derived protein IV (Reg IV). Reg IV is a secretory protein that has garnered attention due to its association with various physiological and pathological processes. Inhibitors within this chemical class are designed to target and regulate the activity of Reg IV, ultimately influencing cellular responses and molecular pathways that are linked to this protein.
Reg IV Inhibitors typically function by binding to Reg IV, its interaction with other cellular components or receptors. This binding process can lead to the downregulation of downstream signaling pathways that rely on Reg IV's activity. By inhibiting the actions of Reg IV, these compounds can potentially impact cellular processes such as cell growth, proliferation, and differentiation. Additionally, the modulation of Reg IV may have implications in the regulation of immune responses and inflammatory reactions, as Reg IV has been found to be involved in certain aspects of these processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG modulates signaling pathways such as PI3K/Akt, which may be related to pathways influenced by REG4, potentially reducing its expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin affects multiple signaling pathways, including NF-κB, which may intersect with REG4-related pathways, leading to a decrease in its expression. | ||||||
Sulindac | 38194-50-2 | sc-202823 sc-202823A sc-202823B | 1 g 5 g 10 g | $32.00 $86.00 $150.00 | 3 | |
As a non-steroidal anti-inflammatory drug, Sulindac impacts prostaglandin synthesis, which may indirectly affect REG4 expression through inflammation-related pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Another PI3K inhibitor, Wortmannin can alter cellular processes that might intersect with REG4's role in cell proliferation or differentiation. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, SP600125 can influence signaling pathways that may also be affected by REG4, leading to altered protein expression. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
This compound inhibits p38 MAPK and can modulate stress response pathways that might intersect with those involving REG4. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
By inhibiting mTOR, Rapamycin can affect cell growth and proliferation pathways, possibly intersecting with REG4-related processes. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
This proteasome inhibitor can lead to altered signaling pathway dynamics that may indirectly influence REG4 activity. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
A compound that affects nucleotide synthesis and can impact cell proliferation, possibly interacting with pathways associated with REG4. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As a histone deacetylase inhibitor, Trichostatin A can change gene expression profiles, potentially affecting REG4 expression indirectly. | ||||||